Department of Ophthalmology, The Affiliated Eye Hospital of Nanjing Medical University, Nanjing 210029, China.
Dis Markers. 2021 Dec 26;2021:6575195. doi: 10.1155/2021/6575195. eCollection 2021.
The vitreous body is an important part of the ocular body fluid. A foldable capsular vitreous body (FCVB) is designed to treat chronic adverse complications in severe ocular trauma and silicone oil-dependent eyes. This study is aimed at investigating a method for implanting an FCVB, its postoperative efficacy, and clinical value.
A retrospective analysis was performed on data from 18 patients who underwent vitrectomy and FCVB implantation for severe ocular trauma and silicone oil-dependent eyes between March 2019 and May 2020. All treated eyes underwent clinical examinations involving the best-corrected visual acuity, intraocular pressure, FCVB position, anterior segment photography, and wide-angle fundus photography regularly after surgery.
Eighteen eyes from 18 patients were enrolled in this study. A total of 2.00-4.20 (3.46 ± 0.78) ml of silicone oil were injected into the FCVB during surgery. The patients were followed up at 1, 2, and 4 weeks and 3, 6, and 12 months after surgery. Twelve months after surgery, visual acuity improved in 7 (38.89%) eyes. In contrast, 10 (55.56%) eyes showed no obvious improvement, and 1 (5.56%) eye had decreased vision. Intraocular pressure at 12 months was 10.13 ± 3.52 mmHg, which was comparable to that before the surgery ( = 0.38, = 0.71). The anterior chamber depth examined by slit lamp was 2.00-3.00 cornea thickness (CT) in 7 eyes, 1.00-2.00 CT in 2 eyes, and <1.00 CT in one eye. The anterior chamber disappeared in eight eyes. There were eight eyes with clear cornea, four eyes with localized opacity, and two eyes with obvious gray-white opacity. There was no case of severe FCVB deflection, rupture, or exposure during the observation period.
FCVB implantation is an effective and safe treatment for eyes with severe ocular trauma and silicone oil-dependent eyes. It may support retinal reattachment, slow down eyeball atrophy, reduce the risk of chronic adverse complications such as corneal endothelial decompensation, and maintain intraocular pressure and preoperative visual function.
玻璃体是眼体液的重要组成部分。折叠式囊玻璃体(FCVB)旨在治疗严重眼外伤和硅油依赖眼中的慢性不良并发症。本研究旨在探讨一种植入 FCVB 的方法、其术后疗效和临床价值。
对 2019 年 3 月至 2020 年 5 月间因严重眼外伤和硅油依赖而行玻璃体切除术和 FCVB 植入术的 18 例患者的资料进行回顾性分析。所有治疗眼术后定期行最佳矫正视力、眼压、FCVB 位置、眼前段照相和广角眼底照相检查。
本研究共纳入 18 例患者的 18 只眼。术中共向 FCVB 内注入 2.00-4.20ml(3.46±0.78ml)硅油。患者分别于术后 1、2、4 周和 3、6、12 个月进行随访。术后 12 个月,视力提高 7 只眼(38.89%),10 只眼(55.56%)无明显改善,1 只眼(5.56%)视力下降。术后 12 个月眼压为 10.13±3.52mmHg,与术前比较差异无统计学意义(=0.38,=0.71)。裂隙灯检查前房深度为 7 只眼 2.00-3.00 角膜厚度(CT),2 只眼 1.00-2.00 CT,1 只眼<1.00 CT。8 只眼前房消失,8 只眼角膜透明,4 只眼角膜局部混浊,2 只眼角膜明显灰白色混浊。观察期间未发生严重 FCVB 偏位、破裂或暴露。
FCVB 植入术是治疗严重眼外伤和硅油依赖眼的有效、安全方法,可支持视网膜复位,减缓眼球萎缩,降低角膜内皮失代偿等慢性不良并发症的风险,维持眼压和术前视功能。