Georgakopoulou Vasiliki Epameinondas, Papalexis Petros, Sanos Christos, Bitsani Aikaterini, Garmpi Anna, Damaskos Christos, Garmpis Nikolaos, Gkoufa Aikaterini, Chlapoutakis Serafeim, Sklapani Pagona, Mantzouranis Konstantinos, Trakas Nikolaos, Spandidos Demetrios A
Pulmonology Department, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
First Department of Propedeutic Internal Medicine, Laiko General Hospital, Medical School, National and Kapodistrian University of Athens, 11527 Athens, Greece.
Biomed Rep. 2021 Dec;15(6):107. doi: 10.3892/br.2021.1483. Epub 2021 Oct 28.
Coronavirus disease (COVID-19) is an infection caused by the newly detected coronavirus, SARS-CoV-2. The majority of individuals will exhibit mild to moderate illness. Older individuals, and those suffering from co-existing diseases have a greater probability of experiencing a serious illness. Moreover, elderly patients have higher mortality rates than younger patients, especially those who are unvaccinated. Asymptomatic infection is mostly observed in individuals who are younger, as younger patients are more likely to exhibit a stronger immune response to the infection; aging is characterized by the decline immune function. In this article, a rare case of an unvaccinated 97-year-old woman is described who was admitted to Laiko General Hospital due to altered levels of consciousness, hypotension and a hematoma of the thoracic region, and tested positive for SARS-CoV-2 nucleic acid in a nasopharyngeal specimen and positive for IgG antibodies against the SARS-CoV-2 spike protein without a history of consistent manifestations, indicating a past asymptomatic infection.
冠状病毒病（COVID-19）是由新发现的冠状病毒SARS-CoV-2引起的一种感染。大多数人会表现出轻度至中度疾病。老年人以及患有并存疾病的人患重病的可能性更大。此外，老年患者的死亡率高于年轻患者，尤其是那些未接种疫苗的患者。无症状感染多见于年轻人，因为年轻患者对感染更有可能表现出更强的免疫反应；衰老的特征是免疫功能下降。本文描述了一例罕见的97岁未接种疫苗的女性病例，该患者因意识水平改变、低血压和胸部血肿入住莱科综合医院，鼻咽标本中SARS-CoV-2核酸检测呈阳性，针对SARS-CoV-2刺突蛋白的IgG抗体检测呈阳性，且无持续症状史，表明既往有无症状感染。
