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利伐沙班大量过量的保守治疗:一例病例报告及文献综述

Conservative management of massive rivaroxaban overdose: A case report and literature review.

作者信息

Ghodsi Alireza, Etemad Leila, Dadpour Bita, Mostafazadeh Babak, Moshiri Mohammad

机构信息

Student Research Committee Faculty of Medicine Mashhad University of Medical Sciences Mashhad Iran.

Pharmaceutical Research Center Pharmaceutical Technology Institute Mashhad University of Medical Sciences Mashhad Iran.

出版信息

Clin Case Rep. 2021 Nov 6;9(11):e05023. doi: 10.1002/ccr3.5023. eCollection 2021 Nov.

DOI:10.1002/ccr3.5023
PMID:34765205
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8572343/
Abstract

In the cases of acute rivaroxaban overdose, conservative management without prothrombin complex concentrate or other coagulation factors may be sufficient if renal function is normal and there is no bleeding.

摘要

在急性利伐沙班过量的情况下,如果肾功能正常且无出血,不使用凝血酶原复合物浓缩物或其他凝血因子的保守治疗可能就足够了。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcb8/8572343/2d0025783974/CCR3-9-e05023-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcb8/8572343/2d0025783974/CCR3-9-e05023-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/fcb8/8572343/2d0025783974/CCR3-9-e05023-g001.jpg

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Expert Opin Pharmacother. 2018 Oct;19(14):1597-1602. doi: 10.1080/14656566.2018.1515913. Epub 2018 Sep 17.
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Anti-factor Xa Monitoring and Activated Charcoal for a Pediatric Patient With Rivaroxaban Overdose.一名服用过量利伐沙班的儿科患者的抗Xa因子监测与活性炭治疗
Clin Pract Cases Emerg Med. 2018 Jul 16;2(3):247-250. doi: 10.5811/cpcem.2018.5.38373. eCollection 2018 Aug.
3
Accidental Rivaroxaban Intoxication in a Boy: Some Lessons in Managing New Oral Anticoagulants in Children.
一名男孩意外服用利伐沙班过量:儿童新型口服抗凝剂管理的一些经验教训。
Pediatr Emerg Care. 2019 Mar;35(3):e44-e46. doi: 10.1097/PEC.0000000000001392.
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Assessing Bleeding Risk in Patients With Intentional Overdoses of Novel Antiplatelet and Anticoagulant Medications.评估新型抗血小板和抗凝药物故意过量服用患者的出血风险。
Ann Emerg Med. 2018 Mar;71(3):273-278. doi: 10.1016/j.annemergmed.2017.08.046. Epub 2017 Oct 9.
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Old and new oral anticoagulants: Food, herbal medicines and drug interactions.新型与传统口服抗凝药:食物、草药及药物相互作用
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