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本文引用的文献

1
Recent Advances in the Development of Stem-Cell-Derived Dopaminergic Neuronal Transplant Therapies for Parkinson's Disease.近年来,基于干细胞的多巴胺能神经元移植疗法治疗帕金森病的研究进展。
Mov Disord. 2021 Aug;36(8):1772-1780. doi: 10.1002/mds.28628. Epub 2021 May 8.
2
Transmissible α-synuclein seeding activity in brain and stomach of patients with Parkinson's disease.帕金森病患者脑和胃中可传播的α-突触核蛋白的种子活性。
Acta Neuropathol. 2021 Jun;141(6):861-879. doi: 10.1007/s00401-021-02312-4. Epub 2021 Apr 24.
3
Genetic Variations and Neuropathologic Features of Patients with PRKN Mutations.PRKN 基因突变患者的遗传变异和神经病理学特征。
Mov Disord. 2021 Jul;36(7):1634-1643. doi: 10.1002/mds.28521. Epub 2021 Feb 11.
4
Prion Diseases: A Unique Transmissible Agent or a Model for Neurodegenerative Diseases?朊病毒病:独特的传染性病原体还是神经退行性疾病的模型?
Biomolecules. 2021 Feb 2;11(2):207. doi: 10.3390/biom11020207.
5
A Phase 1 Randomized Trial of Specific Active α-Synuclein Immunotherapies PD01A and PD03A in Multiple System Atrophy.一项特定的α-突触核蛋白免疫疗法 PD01A 和 PD03A 治疗多系统萎缩的 1 期随机试验。
Mov Disord. 2020 Nov;35(11):1957-1965. doi: 10.1002/mds.28218. Epub 2020 Sep 3.
6
Brain-first versus body-first Parkinson's disease: a multimodal imaging case-control study.脑优先与身体优先的帕金森病:一项多模态成像病例对照研究。
Brain. 2020 Oct 1;143(10):3077-3088. doi: 10.1093/brain/awaa238.
7
Animal Models of Parkinson's Disease: Are They Useful or Not?帕金森病动物模型:它们有用吗?
J Parkinsons Dis. 2020;10(4):1335-1342. doi: 10.3233/JPD-202200.
8
Impact of α-synuclein pathology on transplanted hESC-derived dopaminergic neurons in a humanized α-synuclein rat model of PD.α-突触核蛋白病对对人源化 PD α-突触核蛋白大鼠模型中移植的 hESC 源性多巴胺能神经元的影响。
Proc Natl Acad Sci U S A. 2020 Jun 30;117(26):15209-15220. doi: 10.1073/pnas.2001305117. Epub 2020 Jun 15.
9
Immunization therapies for Parkinson's disease: state of the art and considerations for future clinical trials.帕金森病的免疫治疗:最新进展及对未来临床试验的思考。
Expert Opin Investig Drugs. 2020 Jul;29(7):685-695. doi: 10.1080/13543784.2020.1771693. Epub 2020 Jun 12.
10
Modeling Parkinson's Disease With the Alpha-Synuclein Protein.用α-突触核蛋白模拟帕金森病
Front Pharmacol. 2020 Apr 23;11:356. doi: 10.3389/fphar.2020.00356. eCollection 2020.

The Origins of the Protein Spread in Parkinson's Disease.

作者信息

Barker Roger A

机构信息

Wellcome-MRC Stem Cell institute and Department of Neurology, Addenbrooke's Hospital University of Cambridge Cambridge United Kingdom.

出版信息

Mov Disord Clin Pract. 2021 Aug 23;8(8):1194-1197. doi: 10.1002/mdc3.13314. eCollection 2021 Nov.

DOI:10.1002/mdc3.13314
PMID:34765685
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8564822/
Abstract
摘要