The Origins of the Protein Spread in Parkinson's Disease.
作者信息
Barker Roger A
机构信息
Wellcome-MRC Stem Cell institute and Department of Neurology, Addenbrooke's Hospital University of Cambridge Cambridge United Kingdom.
出版信息
Mov Disord Clin Pract. 2021 Aug 23;8(8):1194-1197. doi: 10.1002/mdc3.13314. eCollection 2021 Nov.
Abstract
摘要
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Transmissible α-synuclein seeding activity in brain and stomach of patients with Parkinson's disease.帕金森病患者脑和胃中可传播的α-突触核蛋白的种子活性。
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Prion Diseases: A Unique Transmissible Agent or a Model for Neurodegenerative Diseases?朊病毒病：独特的传染性病原体还是神经退行性疾病的模型？
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A Phase 1 Randomized Trial of Specific Active α-Synuclein Immunotherapies PD01A and PD03A in Multiple System Atrophy.一项特定的α-突触核蛋白免疫疗法 PD01A 和 PD03A 治疗多系统萎缩的 1 期随机试验。
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J Parkinsons Dis. 2020;10(4):1335-1342. doi: 10.3233/JPD-202200.
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Proc Natl Acad Sci U S A. 2020 Jun 30;117(26):15209-15220. doi: 10.1073/pnas.2001305117. Epub 2020 Jun 15.
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Immunization therapies for Parkinson's disease: state of the art and considerations for future clinical trials.帕金森病的免疫治疗：最新进展及对未来临床试验的思考。
Expert Opin Investig Drugs. 2020 Jul;29(7):685-695. doi: 10.1080/13543784.2020.1771693. Epub 2020 Jun 12.
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