Sen Sumit, Mallick Subhadeep, Das Somnath, Das Jyoti, Sharma Surabhi, Baisya Subhasmita
Department of Dermatology, IPGME&R and SSKM Hospital, Kolkata, West Bengal, India.
Indian J Sex Transm Dis AIDS. 2021 Jan-Jun;42(1):69-72. doi: 10.4103/ijstd.IJSTD_17_20. Epub 2021 Feb 15.
Kaposi's sarcoma (KS) is an angioproliferative disorder primarily of viral etiology, though multiple cofactors are also responsible. Human herpes virus-8, a gamma herpes virus, is considered to be the causative agent. Acquired immunodeficiency syndrome-associated KS has different clinical pictures than those seen in other types of KS. As it progresses rapidly, early institution of highly active antiretroviral therapy (HAART) after proper diagnosis is expected. Though HAART has reduced the prevalence of KS in HIV disease, HAART has not eliminated the disease. Here, we report a case who is HIV 1 and hepatitis B surface antigen positive with numerous violaceous plaques over the face, upper extremities, and trunk along with oral mucosal involvement. He had received ten sessions of electron beam radiotherapy on the face, and the facial lesions have healed with residual hyperpigmentation.
卡波西肉瘤(KS)是一种主要由病毒病因引起的血管增生性疾病,不过多种辅助因素也起作用。人疱疹病毒8型,一种γ疱疹病毒,被认为是病原体。获得性免疫缺陷综合征相关的卡波西肉瘤与其他类型的卡波西肉瘤有不同的临床表现。由于其进展迅速,在正确诊断后预期应尽早开始高效抗逆转录病毒治疗(HAART)。尽管HAART降低了卡波西肉瘤在HIV疾病中的患病率,但HAART并未消除该疾病。在此,我们报告一例HIV 1和乙肝表面抗原阳性的病例,其面部、上肢和躯干有大量紫罗兰色斑块,并伴有口腔黏膜受累。他面部接受了十次电子束放射治疗,面部病变已愈合,留有色素沉着。