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卡波西肉瘤:病例报告及治疗选择

Kaposi's sarcoma: case report and treatment options.

作者信息

Tan W C, Chan L C

机构信息

Department of Dermatology, Hospital Pulau Pinang, Penang, Malaysia.

出版信息

Med J Malaysia. 2011 Oct;66(4):383-4.

Abstract

Kaposi's sarcoma (KS) is strongly associated with Human Herpes Virus 8 (HHV8) and Human Immunodeficiency Virus infection (HIV). It was the first malignancy to be linked with Acquired Immunodeficiency Syndrome (AIDS). We report a case of Kaposi's sarcoma in a newly diagnosed retroviral homosexual patient with CD4 count of 21. He had multiple firm discrete violaceous plaques and nodules scattered over the face, scalp, hard palate, trunk and genitalia. Biopsy of a skin nodule over the trunk and a biopsy of a lesion from the gastric mucosa confirmed Kaposi's sarcoma. He was started on Highly Active Antiretroviral Therapy (HAART) and cryotherapy (liquid nitrogen) was given for the lesions over the skin. He responded well to treatment. Liquid nitrogen is a useful adjuvant treatment for Kaposi's sarcoma.

摘要

卡波西肉瘤(KS)与人类疱疹病毒8型(HHV8)和人类免疫缺陷病毒感染(HIV)密切相关。它是首例与获得性免疫缺陷综合征(AIDS)相关的恶性肿瘤。我们报告一例新诊断的逆转录病毒感染同性恋患者的卡波西肉瘤病例,其CD4细胞计数为21。他面部、头皮、硬腭、躯干和生殖器散在多个坚实、孤立的紫罗兰色斑块和结节。对躯干上的一个皮肤结节以及胃黏膜病变进行活检,确诊为卡波西肉瘤。他开始接受高效抗逆转录病毒治疗(HAART),并对皮肤上的病变进行了冷冻疗法(液氮)治疗。他对治疗反应良好。液氮是治疗卡波西肉瘤的一种有用辅助疗法。

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