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COVID-19 vaccination can occasionally trigger autoimmune phenomena, probably via inducing age-associated B cells.新冠病毒疫苗接种偶尔会引发自身免疫现象，可能是通过诱导与年龄相关的B细胞来实现的。
Int J Rheum Dis. 2022 Jan;25(1):83-85. doi: 10.1111/1756-185X.14238. Epub 2021 Nov 12.
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COVID-19 vaccination can occasionally trigger autoimmune phenomena, probably via inducing age-associated B cells.新冠病毒疫苗接种偶尔会引发自身免疫现象，可能是通过诱导与年龄相关的B细胞来实现的。
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本文引用的文献

1
Double Negative (DN) B cells: A connecting bridge between rheumatic diseases and COVID-19?双阴性（DN）B细胞：风湿性疾病与2019冠状病毒病之间的桥梁？
Mediterr J Rheumatol. 2021 Sep 30;32(3):192-199. doi: 10.31138/mjr.32.3.192. eCollection 2021 Sep.
2
Disease Flare and Reactogenicity in Patients With Rheumatic and Musculoskeletal Diseases Following Two-Dose SARS-CoV-2 Messenger RNA Vaccination.风湿和肌肉骨骼疾病患者在接受两剂 SARS-CoV-2 信使 RNA 疫苗接种后的疾病发作和反应原性。
Arthritis Rheumatol. 2022 Jan;74(1):28-32. doi: 10.1002/art.41924. Epub 2021 Dec 3.
3
Immune-Mediated Disease Flares or New-Onset Disease in 27 Subjects Following mRNA/DNA SARS-CoV-2 Vaccination.27名受试者在接种mRNA/DNA新冠病毒疫苗后出现免疫介导疾病发作或新发疾病
Vaccines (Basel). 2021 Apr 29;9(5):435. doi: 10.3390/vaccines9050435.
4
COVID-19 vaccines: modes of immune activation and future challenges.COVID-19 疫苗：免疫激活模式和未来挑战。
Nat Rev Immunol. 2021 Apr;21(4):195-197. doi: 10.1038/s41577-021-00526-x.
5
Specific Induction of Double Negative B Cells During Protective and Pathogenic Immune Responses.保护性和致病性免疫应答期间双阴性 B 细胞的特异性诱导。
Front Immunol. 2020 Dec 18;11:606338. doi: 10.3389/fimmu.2020.606338. eCollection 2020.
6
Age-Associated B Cells (ABCs) in the Prognosis, Diagnosis and Therapy of Systemic Lupus Erythematosus (SLE).衰老相关B细胞（ABCs）在系统性红斑狼疮（SLE）预后、诊断及治疗中的作用
Mediterr J Rheumatol. 2020 Sep 30;31(3):311-318. doi: 10.31138/mjr.31.3.311. eCollection 2020 Sep.
7
Extrafollicular B cell responses correlate with neutralizing antibodies and morbidity in COVID-19.滤泡外 B 细胞反应与 COVID-19 中的中和抗体和发病相关。
Nat Immunol. 2020 Dec;21(12):1506-1516. doi: 10.1038/s41590-020-00814-z. Epub 2020 Oct 7.
8
Age-Associated B Cells.与年龄相关的 B 细胞。
Annu Rev Immunol. 2020 Apr 26;38:315-340. doi: 10.1146/annurev-immunol-092419-031130. Epub 2020 Jan 27.
9
Generation of functional murine CD11c age-associated B cells in the absence of B cell T-bet expression.在缺乏 B 细胞 T-bet 表达的情况下生成功能性小鼠 CD11c 年龄相关 B 细胞。
Eur J Immunol. 2019 Jan;49(1):170-178. doi: 10.1002/eji.201847641. Epub 2018 Nov 5.
10
Distinct Effector B Cells Induced by Unregulated Toll-like Receptor 7 Contribute to Pathogenic Responses in Systemic Lupus Erythematosus.未调节的 Toll 样受体 7 诱导的效应 B 细胞导致系统性红斑狼疮的致病性反应。
Immunity. 2018 Oct 16;49(4):725-739.e6. doi: 10.1016/j.immuni.2018.08.015. Epub 2018 Oct 9.

COVID-19 vaccination can occasionally trigger autoimmune phenomena, probably via inducing age-associated B cells.

作者信息

Sachinidis Athanasios, Garyfallos Alexandros

机构信息

4th Department of Internal Medicine, School of Medicine, Hippokration General Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.

出版信息

Int J Rheum Dis. 2022 Jan;25(1):83-85. doi: 10.1111/1756-185X.14238. Epub 2021 Nov 12.

DOI:10.1111/1756-185X.14238
PMID:34766739
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8652459/
Abstract
摘要