School of Population Health, Curtin University, Bentley, WA, Australia.
Ear Science Institute Australia, 1 Salvado Road, Subiaco, WA, 6008, Australia.
Trials. 2021 Nov 12;22(1):793. doi: 10.1186/s13063-021-05714-7.
There is an urgent need to develop new therapies to improve cognitive function in adults following cochlear implant surgery. This study aims to determine if completing at-home computer-based brain training activities improve memory and thinking skills in adults following their first cochlear implant.
This study will be conducted as a single-blind, head-to-head, randomised controlled trial (RCT). It will determine whether auditory training combined with adaptive computerised cognitive training will elicit greater improvement in cognition, sound and speech perception, mood, and quality of life outcomes in adult cochlear implant recipients, when compared to auditory training combined with non-adaptive (i.e. placebo) computerised cognitive training. Participants 18 years or older who meet the clinical criteria for a cochlear implant will be recruited into the study.
The results of this trial will clarify whether the auditory training combined with cognitive training will improve cognition, sound and speech perception, mood, and quality of life outcomes in adult cochlear implant recipients.
We anticipate that our findings will have implications for clinical practice in the treatment of adult cochlear implant recipients.
Australian New Zealand Clinical Trials Registry ACTRN12619000609156 . Registered on April 23 2019.
迫切需要开发新的疗法，以改善成年人工耳蜗植入术后的认知功能。本研究旨在确定在家中完成基于计算机的大脑训练活动是否会改善首次接受人工耳蜗植入的成年人的记忆和思维能力。
本研究将作为一项单盲、头对头、随机对照试验（RCT）进行。它将确定听觉训练与自适应计算机认知训练相结合是否会比听觉训练与非自适应（即安慰剂）计算机认知训练更能改善成年人工耳蜗植入者的认知、声音和言语感知、情绪和生活质量。将招募年龄在 18 岁或以上符合人工耳蜗植入临床标准的参与者参加这项研究。
这项试验的结果将阐明听觉训练与认知训练相结合是否会改善成年人工耳蜗植入者的认知、声音和言语感知、情绪和生活质量。
我们预计我们的发现将对成年人工耳蜗植入者的治疗的临床实践产生影响。
澳大利亚新西兰临床试验注册中心 ACTRN12619000609156。于 2019 年 4 月 23 日注册。
