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[休克中的止血障碍]

[Disorders of hemostasis in shock].

作者信息

Heinrichs C

出版信息

Z Gesamte Inn Med. 1978 Mar 15;33(6):169-75.

PMID:347730
Abstract

Shock and disturbance of haemostasis are described as the cause of a common severe basic disease evoking them. Haemodynamically rheological changes with disturbances of the perfusion of high degree which in the extreme case via formations of microcoagulations may lead to organ necroses with irreversible deleterius loss of organs are common to both. Bodily dysregulations may also lead to an increase of the potential of fibrinolysis with dramatic haemorrhagic complications. A coarsely orienting stage division of the consumption coagulopathy allows aimed therapeutic measures after differentiated indication, such as the application of antifibrinolytics and aimed haemosubstitution under heparin protection.

摘要

休克和止血功能紊乱被描述为引发它们的一种常见严重基础疾病的病因。血流动力学流变学变化伴有高度灌注紊乱,在极端情况下,通过微凝血的形成可能导致器官坏死以及器官不可逆转的有害性丧失,这两者是共有的。身体调节功能紊乱也可能导致纤维蛋白溶解潜能增加并伴有严重的出血并发症。对消耗性凝血病进行大致的阶段划分,有助于在明确指征后采取针对性的治疗措施,例如应用抗纤维蛋白溶解剂以及在肝素保护下进行针对性的血液置换。

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