Department of Cardiac Surgery, University of Michigan, Ann Arbor, Michigan.
Department of Cardiac Surgery, University of Michigan, Ann Arbor, Michigan.
Ann Thorac Surg. 2022 Dec;114(6):2163-2171. doi: 10.1016/j.athoracsur.2021.09.065. Epub 2021 Nov 10.
Various surgical options have been described for the treatment of aberrant subclavian arteries and an associated Kommerell diverticulum.
Between 1999 and 2019, 43 patients underwent a repair, comprising 26 (61%) endovascular and 17 (39%) open approaches. The endovascular approach consisted of initial subclavian revascularization followed by thoracic endovascular aortic repair. The open approach included total arch replacement (12%) and reverse hemiarch repair with left thoracotomy (53%) or right thoracotomy (35%). The perioperative and long-term outcomes were retrospectively reviewed.
No mortality occurred in the endovascular group, whereas there was 1 (6%) in the open approach group. Patients in the endovascular group demonstrated a shorter hospital stay (3.5 days vs 10.0 days; P = .001) and less frequent prolonged mechanical ventilation (0% vs 24%; P = .019), with a lower occurrence of pneumonia (0% vs 24%; P = .019). Among patients who had the endovascular approach, shrinkage of Kommerell diverticulum or aberrant vessel origin was seen in 96%. Furthermore, relief of dysphagia was confirmed in 92% (12/13), including patients without Kommerell diverticulum (n = 3) after endovascular repair. The cumulative incidence of treatment failure or aortic reintervention at 7 years was 21% and 14 % in the endovascular and open approach groups, respectively (P = .62). Two (8%) patients in the endovascular group required an open reintervention. One reintervention was performed for persistent dysphagia in the setting of an untreated complete vascular ring, and the other was for persistent false lumen flow associated with aortic dissection.
The treatment approach should be individualized on the basis of the aortic disease and comorbidities. The endovascular approach is a viable and effective alternative in the presence of suitable landing zones.
对于异常锁骨下动脉和相关 Kommerell 憩室,已经描述了各种手术选择。
1999 年至 2019 年,43 名患者接受了修复手术,其中 26 例(61%)采用血管内方法,17 例(39%)采用开放方法。血管内方法包括锁骨下动脉再血管化,然后进行胸主动脉腔内修复。开放方法包括全弓置换术(12%)和反向半弓修复术,其中左侧开胸术(53%)或右侧开胸术(35%)。回顾性分析围手术期和长期结果。
血管内组无死亡,而开放组有 1 例(6%)。血管内组患者的住院时间更短(3.5 天比 10.0 天;P=0.001),机械通气时间延长的发生率更低(0%比 24%;P=0.019),肺炎的发生率也更低(0%比 24%;P=0.019)。接受血管内治疗的患者中,Kommerell 憩室或异常血管起源的缩小率为 96%。此外,13 例患者中有 12 例(92%)的吞咽困难得到缓解,包括血管内修复后无 Kommerell 憩室的 3 例患者。血管内组和开放组的 7 年治疗失败或主动脉再干预的累积发生率分别为 21%和 14%(P=0.62)。血管内组有 2 例(8%)患者需要进行开放再干预。1 例是由于未治疗的完全血管环导致持续性吞咽困难,另 1 例是由于主动脉夹层相关的假腔血流持续存在。
治疗方法应根据主动脉疾病和合并症进行个体化。在有合适的着陆区的情况下,血管内方法是一种可行且有效的替代方法。