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基于支架移植物的治疗使Kommerell憩室的动脉瘤大小缩小。

Aneurysmal size reduction in the Kommerell diverticulum by stent graft-based therapy.

作者信息

Inno Goki, Takahashi Yosuke, Morisaki Akimasa, Nishiya Kenta, Kawase Takumi, Nishimoto Yukihiro, Noda Kazuki, Nagao Munehide, Nangoya Ryo, Shibata Toshihiko

机构信息

Department of Cardiovascular Surgery, Osaka Metropolitan University Graduate School of Medicine, Osaka, Japan.

出版信息

J Thorac Dis. 2025 Feb 28;17(2):1064-1072. doi: 10.21037/jtd-24-1709. Epub 2025 Feb 25.

Abstract

Kommerell diverticulum (KD) with an aberrant subclavian artery is a rare congenital anomaly that often resembles a saccular aneurysm. Open surgery is the traditional treatment; however, recent reports have suggested success with endovascular or hybrid approaches. This study aimed to show the results of stent graft-based treatment and demonstrate the aneurysmal reduction rate in KD. Five patients with KD underwent stent graft-based therapy at the Osaka Metropolitan University Hospital between May 2009 and February 2024. Patient data and KD measurements were retrospectively analyzed using computed tomography scans. Two indices were measured to assess the size of the KD: (I) the distance from the tip of the KD to the opposite aortic wall (DAW), which is often used to assess KD size; (II) the height of the KD from the original virtual normal aortic wall, as in the evaluation of saccular aneurysms. The mean observation period after surgery was 62.4±36.9 months. Postoperative remodeling of the KD was assessed in these five cases. One patient underwent 1-debranch thoracic endovascular aortic repair, and four patients underwent the frozen elephant trunk (FET) technique via median sternotomy. On average, DAW was reduced to 76.1%±9.5% and the height of KD, the height of the protrusion from the normal aortic wall, was reduced to 31.0%±23.8%. None of the five cases required rehospitalization or reintervention. None of the patients died, and the KD was greatly reduced in size. Treatment using stent grafts greatly reduced the size of the KD. Decompression of KD is likely to lead to remodeling of the aortic wall, which constitutes KD.

摘要

伴有异常锁骨下动脉的Kommerell憩室(KD)是一种罕见的先天性异常,常类似囊状动脉瘤。开放手术是传统治疗方法;然而,最近的报告表明血管内或杂交方法取得了成功。本研究旨在展示基于支架移植物治疗的结果,并证明KD的动脉瘤缩小率。2009年5月至2024年2月期间,五名KD患者在大阪市立大学医院接受了基于支架移植物的治疗。使用计算机断层扫描对患者数据和KD测量值进行回顾性分析。测量了两个指标来评估KD的大小:(I)KD尖端到对侧主动脉壁的距离(DAW),这常用于评估KD大小;(II)KD相对于原始虚拟正常主动脉壁的高度,如同评估囊状动脉瘤一样。术后平均观察期为62.4±36.9个月。对这五例患者的KD术后重塑情况进行了评估。一名患者接受了1分支胸主动脉腔内修复术,四名患者通过正中胸骨切开术采用了冰冻象鼻技术(FET)。平均而言,DAW降至76.1%±9.5%,KD的高度,即从正常主动脉壁突出的高度,降至31.0%±23.8%。五例患者均无需再次住院或再次干预。患者均未死亡,KD大小大幅缩小。使用支架移植物治疗大大减小了KD的大小。KD减压可能会导致构成KD的主动脉壁重塑。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a23d/11898329/e7bf2e8a02f3/jtd-17-02-1064-f1.jpg

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