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体质指数与 45 个中低收入国家青少年自杀意念和自杀未遂风险的关系。

Body mass index and the risk of suicidal ideation and suicide attempt among youth in 45 low-and middle-income countries.

机构信息

School of Health Sciences, Wuhan University, Donghu Rd, No. 185, Wuhan, Hubei Province 430071, PR China.

School of Health Sciences, Wuhan University, Donghu Rd, No. 185, Wuhan, Hubei Province 430071, PR China; Hubei Biomass-Resource Chemistry and Environmental Biotechnology Key Laboratory, Wuhan University, Wuhan, PR China.

出版信息

J Affect Disord. 2022 Feb 1;298(Pt A):357-363. doi: 10.1016/j.jad.2021.11.018. Epub 2021 Nov 10.

Abstract

BACKGROUND

Suicide has become a severe public health issue worldwide. Body weight has been put forward as a potentially modifiable element for suicide thought and behavior. However, there are discrepancies across previous studies. Furthermore, the relationships of body weight with suicidal ideation and suicide attempt among low- and middle-income countries (LMICs) remain unclear. Therefore, we addressed this issue among 104,907 adolescents of 12-15 years old in 45 LMICs.

METHODS

The present study used data from the Global School-based Student Health Survey (GSHS). Suicidal ideation and suicide attempt during the last year were self-reported. Participants were classified intro underweight, normal weight, overweight and obesity according to their body mass index classification. Multivariable logistic regression and meta-analyses based on country-wise estimates were conducted.

RESULTS

The prevalence of suicidal ideation and suicide attempt were 11.8% and 13.0%, respectively. Countrywide meta-analysis demonstrated that overweight and obesity were significantly associated with increased risks of suicidal ideation (For overweight: OR = 1.10; 95% CI = 1.01-1.20; for obesity: OR=1.17; 95%CI: 1.01-1.35) and suicide attempt (For overweight: OR = 1.12; 95% CI = 1.02-1.23; for obesity: OR=1.12; 95%CI: 1.00-1.25). Subgroup analyses showed that the associations between overweight/obesity and suicide attempt were significant for girls but not for boys.

LIMITATIONS

The cross-sectional design cannot explore causality; mental health factors were not assessed; suicidal behaviors were self-reported; significant heterogeneity across countries; only students attending school were included.

CONCLUSIONS

Overweight/obesity was significantly associated with the risk of suicidal ideation and suicide attempt among adolescents in LMICs.

摘要

背景

自杀已成为全球严重的公共卫生问题。体重已被提出作为自杀意念和行为的一个潜在可改变因素。然而,此前的研究结果存在差异。此外,体重与中低收入国家(LMICs)青少年自杀意念和自杀企图之间的关系仍不清楚。因此,我们在 45 个 LMIC 地区的 104907 名 12-15 岁青少年中研究了这一问题。

方法

本研究使用了来自全球学校学生健康调查(GSHS)的数据。自杀意念和自杀企图是在过去一年中自我报告的。参与者根据他们的体重指数分类分为体重不足、正常体重、超重和肥胖。基于国家层面的估计,进行了多变量逻辑回归和荟萃分析。

结果

自杀意念和自杀企图的发生率分别为 11.8%和 13.0%。全国范围内的荟萃分析表明,超重和肥胖与自杀意念的风险增加显著相关(超重:OR=1.10;95%CI=1.01-1.20;肥胖:OR=1.17;95%CI=1.01-1.35)和自杀企图(超重:OR=1.12;95%CI=1.02-1.23;肥胖:OR=1.12;95%CI=1.00-1.25)。亚组分析表明,超重/肥胖与自杀企图的关联在女孩中显著,但在男孩中不显著。

局限性

横断面设计无法探讨因果关系;未评估心理健康因素;自杀行为是自我报告的;各国之间存在显著的异质性;仅包括在校学生。

结论

超重/肥胖与 LMIC 青少年自杀意念和自杀企图的风险显著相关。

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