Human Movement Performance Enhancement Research Unit, Department of Physical Therapy, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok, 10330, Thailand.
Human Movement Performance Enhancement Research Unit, Department of Physical Therapy, Faculty of Allied Health Sciences, Chulalongkorn University, Bangkok, 10330, Thailand.
J Bodyw Mov Ther. 2021 Oct;28:164-171. doi: 10.1016/j.jbmt.2021.07.013. Epub 2021 Aug 8.
This study sought to investigate the effects of foam pad balance exercises on balance, physical performance, peripheral neuropathy symptoms, and quality of life in cancer patients undergoing taxane-based chemotherapy.
Thirty cancer patients receiving chemotherapy were randomly divided into 2 groups (n = 15/group): control group (CG) and balance exercise group (BG). The BG were asked to perform foam pad balance exercises 60 min/day, twice/week for 6 weeks, along with conventional therapy. The CG only received conventional therapy. The Fullerton Advanced Balance (FAB) Score, Short Physical Performance Battery (SPPB), Michigan Diabetic Neuropathy Score (MDNS), and Functional Assessment of Cancer Therapy-Taxane (FACT-Taxane) were used to assess balance, physical performance, peripheral neuropathy symptoms, and quality of life, respectively, at baseline and after 4 and 6 weeks of treatment.
At 4 and/or 6 weeks, the CG showed a decline in FAB and SPPB Scores, while the BG maintained their baseline levels. There were significant differences in the FAB Scores between the groups at the 4th and 6th week (p = 0.04 and p < 0.01, respectively) and significant differences in SPPB Scores at only the 6th week (p = 0.03). MDNS showed no significant changes between or within groups. For FACT-Taxane between groups, the CG and BG showed significant decreases (p < 0.01) and increases (p < 0.01), respectively, at 6th week.
Foam pad balance exercises during chemotherapy can be used to alleviate declining balance and enhance physical performance and quality of life of cancer patients.
本研究旨在探讨泡沫垫平衡练习对接受紫杉烷类化疗的癌症患者平衡、身体表现、周围神经病症状和生活质量的影响。
30 名接受化疗的癌症患者被随机分为 2 组（n=15/组）：对照组（CG）和平衡运动组（BG）。要求 BG 每天进行 60 分钟的泡沫垫平衡练习，每周两次，共 6 周，同时接受常规治疗。CG 仅接受常规治疗。使用 Fullerton 高级平衡（FAB）评分、简短身体表现电池（SPPB）、密歇根糖尿病神经病变评分（MDNS）和癌症治疗-紫杉烷功能性评估（FACT-Taxane）分别评估基线时和治疗 4 周和 6 周后的平衡、身体表现、周围神经病症状和生活质量。
在 4 周和/或 6 周时，CG 的 FAB 和 SPPB 评分下降，而 BG 保持基线水平。第 4 周和第 6 周时，两组之间的 FAB 评分存在显著差异（p=0.04 和 p<0.01），仅在第 6 周时 SPPB 评分存在显著差异（p=0.03）。MDNS 组间和组内均无显著变化。FACT-Taxane 组间，CG 和 BG 分别在第 6 周时显著下降（p<0.01）和显著增加（p<0.01）。
化疗期间使用泡沫垫平衡练习可以减轻癌症患者平衡下降，增强身体表现和生活质量。
