Division of Respiratory Medicine, Department of Internal Medicine, the Jikei University School of Medicine, Japan.
Department of Otorhinolaryngology, the Jikei University School of Medicine, Japan.
Intern Med. 2022 Jun 15;61(12):1877-1880. doi: 10.2169/internalmedicine.8596-21. Epub 2021 Nov 13.
We herein report two cases of cerebrospinal fluid (CSF) rhinorrhea associated with lung infiltrates. One patient presented with symptomatic non-resolving pneumonia, while the other was asymptomatic. In both cases, the lung infiltrates completely resolved when CSF leakage had subsided. Pulmonary involvement in CSF rhinorrhea is under-recognized, and despite being the definitive treatment, surgery for CSF rhinorrhea is typically postponed due to the presence of lung infiltrates. However, meningitis is a serious complication due to a delay in surgical management. Physicians should be made aware that CSF rhinorrhea is a potential cause of intractable lung infiltrates.
我们在此报告两例与肺部浸润相关的脑脊液（CSF）鼻漏。一例患者表现为有症状的持续性肺炎，另一例患者无症状。在这两种情况下，当脑脊液漏停止时，肺部浸润完全消退。CSF 鼻漏的肺部受累认识不足，尽管手术是明确的治疗方法，但由于存在肺部浸润，通常会推迟 CSF 鼻漏的手术治疗。然而，由于手术管理的延迟，脑膜炎是一种严重的并发症。医生应该意识到 CSF 鼻漏是难治性肺部浸润的潜在原因。
