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作为海绵体脓肿的一种新型致病病原体。

as a novel causative pathogen of cavernosal abscess.

作者信息

Toyoshima Hirokazu, Shibahara Takuji, Tanigawa Motoaki, Masuda Naoto, Ishiguro Chiaki, Tanaka Hiroyuki, Nakanishi Yuki, Sakabe Shigetoshi

机构信息

Department of Infectious Diseases, Japanese Red Cross Ise Hospital, 1-471-2, Funae, Ise, Mie 516-8512, Japan.

Department of Urology, Japanese Red Cross Ise Hospital, 1-471-2, Funae, Ise, Mie 516-8512, Japan.

出版信息

IDCases. 2021 Oct 27;26:e01320. doi: 10.1016/j.idcr.2021.e01320. eCollection 2021.

DOI:10.1016/j.idcr.2021.e01320
PMID:34777993
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8577437/
Abstract

Most cases of cavernosal abscesses result from the progression of sexually transmitted diseases (STDs) commonly caused by ; however, cavernosal abscesses without STDs are rare events. Herein, we describe the first case report of a cavernosal abscess. A 63-year-old man with diabetes and a history of foreign object insertion into the urethra one year prior presented with high-grade fever and slight local pain. The patient was diagnosed with . cavernosal abscess based on computed tomography and microbial biochemical examinations in addition to matrix-assisted laser desorption ionization (MALDI) and 16S rRNA sequencing from blood and pus cultures. The patient was successfully treated with a surgical procedure and appropriate antimicrobials. Hence, . , a commensal bacterium of the gastrointestinal or genitourinary tract, can cause cavernosal abscesses. Notably, . is difficult to distinguish from . using MALDI or 16S rRNA sequencing without microbial biochemical examinations owing to morphological similarities. Therefore, special attention should be paid, clinically and microbiologically, to the potential of . cavernosal abscess in clinical settings.

摘要

大多数海绵体脓肿由常见的性传播疾病(STD)进展引起;然而,无STD的海绵体脓肿是罕见事件。在此,我们描述首例海绵体脓肿病例报告。一名63岁男性,有糖尿病史,一年前有尿道异物插入史,出现高热和轻微局部疼痛。除了血液和脓液培养的基质辅助激光解吸电离(MALDI)和16S rRNA测序外,基于计算机断层扫描和微生物生化检查,该患者被诊断为海绵体脓肿。患者通过手术和适当的抗菌药物成功治疗。因此,[此处有缺失信息,原文未完整给出相关细菌名称],一种胃肠道或泌尿生殖道的共生细菌,可引起海绵体脓肿。值得注意的是,由于形态相似,在没有微生物生化检查的情况下,使用MALDI或16S rRNA测序很难将[此处有缺失信息,原文未完整给出相关细菌名称]与[此处有缺失信息,原文未完整给出相关细菌名称]区分开来。因此,在临床和微生物学方面,应特别关注临床环境中[此处有缺失信息,原文未完整给出相关细菌名称]引起海绵体脓肿的可能性。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b592/8577437/dc4f230c05d9/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b592/8577437/c46ed2cab624/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b592/8577437/56d9ea70f903/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b592/8577437/11cafac513de/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b592/8577437/dc4f230c05d9/gr4.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b592/8577437/c46ed2cab624/gr1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b592/8577437/56d9ea70f903/gr2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b592/8577437/11cafac513de/gr3.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b592/8577437/dc4f230c05d9/gr4.jpg

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