环丙沙星在房水中的渗透情况。
Penetration of ciprofloxacin into aqueous humor.
作者信息
Fern A I, Sweeney G, Doig M, Lindsay G
机构信息
Ophthalmology Department, Southern General Hospital, Glasgow.
出版信息
Trans Ophthalmol Soc U K (1962). 1986;105 ( Pt 6):650-2.
PMID:3477893
Abstract
Ciprofloxacin is a potentially useful antibiotic in eye infection. A pilot study was performed on 25 patients undergoing routine cataract surgery to assess the penetration of the drug into aqueous humor after oral administration. The mean peak level of 0.56 mg/l achieved in aqueous is above the MIC for most gram negative organisms, including Pseudomonas aeruginosa.
摘要
环丙沙星在眼部感染中可能是一种有用的抗生素。对25例接受常规白内障手术的患者进行了一项初步研究，以评估口服给药后药物在房水中的渗透情况。房水中达到的平均峰值水平为0.56毫克/升，高于包括铜绿假单胞菌在内的大多数革兰氏阴性菌的最低抑菌浓度。
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