细胞培养技术和基因工程在未来食品生产和作物改良中的应用，以加强粮食安全。

Application of cell culture technology and genetic engineering for production of future foods and crop improvement to strengthen food security.

机构信息

Department of Food and Agricultural Product Technology, Universitas Gadjah Mada, Yogyakarta, Indonesia.

Faculty of Life Science, Food Nutrition and Health, Food Metabolome, Universitat Bayreuth, Kulmbach, 95326, Germany.

出版信息

Bioengineered. 2021 Dec;12(2):11305-11330. doi: 10.1080/21655979.2021.2003665.

DOI:10.1080/21655979.2021.2003665

PMID:34779353

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8810126/

Abstract

The growing population and the climate changes put a pressure on food production globally, therefore a fundamental transformation of food production is required. One approach to accelerate food production is application of modern biotechnology such as cell culture, marker assisted selection, and genetic engineering. Cell culture technology reduces the usage of arable land, while marker-assisted selection increases the genetic gain of crop breeding and genetic engineering enable to introduce a desired traits to crop. The cell culture technology has resulted in development of cultured meat, fungal biomass food (mycoprotein), and bioactive compounds from plant cell culture. Except cultured meat which recently begin to penetrate the market, the other products have been in the market for years. The marker-assisted selection and genetic engineering have contributed significantly to increase the resiliency against emerging pests and abiotic stresses. This review addresses diverse techniques of cell culture technology as well as advanced genetic engineering technology CRISPR Cas-9 and its application for crop improvement. The pros and cons of different techniques as well as the challenges and future perspective of application of modern biotechnology for strengthening food security are also discussed.

摘要

不断增长的人口和气候变化给全球粮食生产带来了压力，因此需要对粮食生产进行根本性的变革。加速粮食生产的一种方法是应用现代生物技术，如细胞培养、标记辅助选择和基因工程。细胞培养技术减少了耕地的使用，而标记辅助选择增加了作物育种的遗传增益，基因工程则使作物能够引入所需的特性。细胞培养技术已经开发出了培养肉、真菌生物质食品（真菌蛋白）和植物细胞培养的生物活性化合物。除了最近开始进入市场的培养肉，其他产品已经在市场上销售多年。标记辅助选择和基因工程显著提高了对新出现的病虫害和非生物胁迫的抵抗力。本综述介绍了细胞培养技术的多种技术以及先进的基因工程技术 CRISPR Cas-9 及其在作物改良中的应用。还讨论了不同技术的优缺点，以及应用现代生物技术加强粮食安全的挑战和未来前景。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8620/8810126/5d0213a019e5/KBIE_A_2003665_F0001_OC.jpg

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细胞培养技术和基因工程在未来食品生产和作物改良中的应用，以加强粮食安全。

Application of cell culture technology and genetic engineering for production of future foods and crop improvement to strengthen food security.

机构信息

出版信息

相似文献

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本文引用的文献

细胞培养技术和基因工程在未来食品生产和作物改良中的应用，以加强粮食安全。

Application of cell culture technology and genetic engineering for production of future foods and crop improvement to strengthen food security.

机构信息

出版信息

相似文献

引用本文的文献

本文引用的文献