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9 岁男孩以非典型临床表现起病,未被检出的尤文样肉瘤呈现致死性病程。

Fatal course of undetected Ewing-like sarcoma in a 9-year-old boy with uncharacteristic clinical presentation.

机构信息

Department of Forensic Medicine, Paris-Lodron University of Salzburg, Salzburg, Austria.

Institute of Pathology, Paracelsus Medical University Salzburg, Salzburg, Austria.

出版信息

Forensic Sci Med Pathol. 2022 Sep;18(3):231-239. doi: 10.1007/s12024-021-00437-2. Epub 2021 Nov 15.

Abstract

A 9-year-old boy collapsed shortly after complaining of shortness of breath. Despite immediate resuscitation measures, the boy died. A few weeks earlier, he had received antibiotic treatment for respiratory infection. However, the post-mortem examination revealed an advanced tumor mass of the mediastinum with infiltration of vital structures, which was identified as a small blue round neoplasm with aspects of an extramedullary Ewing-like sarcoma by supplementary histological and immunohistochemical examinations.This dramatic clinical course of events shows that the possible presence of serious diseases should always be considered behind harmless symptoms, even in children.

摘要

一名 9 岁男孩在抱怨呼吸急促后不久突然晕倒。尽管立即进行了复苏措施,但男孩还是死亡了。几周前,他曾因呼吸道感染接受过抗生素治疗。然而,尸检显示纵隔内有一个晚期肿瘤块,侵犯了重要结构,通过补充组织学和免疫组织化学检查,该肿瘤被确定为具有髓外尤文样肉瘤特征的小蓝圆形圆形肿瘤。这一戏剧性的临床病程表明,即使是儿童,即使症状看似无害,也始终应该考虑到严重疾病的可能存在。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/a71c/9587088/cb2cc9a6f180/12024_2021_437_Fig1_HTML.jpg

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