Guy's & St Thomas' NHS Foundation Trust, London, UK.
King's College London, London, UK.
Transpl Int. 2021 Oct;34(10):1770-1775. doi: 10.1111/tri.13979. Epub 2021 Sep 19.
As SARS-CoV-2 vaccines have started to be rolled out, a key question facing transplant units has been whether listing for transplantation should be contingent on recipients having received a vaccine. We aimed to provide an ethical framework when considering potential transplant candidates who decline vaccination. We convened a working group comprising transplant professionals, lay members and patients and undertook a literature review and consensus process. This group's work was also informed by discussions in two hospital clinical ethics committees. We have reviewed arguments for and against mandating vaccination prior to listing for kidney transplantation and considered some practical difficulties which may be associated with a policy of mandated vaccination. Rather than requiring that all patients must receive the SARS-CoV-2 vaccine prior to transplant listing, we recommend considering vaccination status as one of a number of SARS-CoV-2-related risk factors in relation to transplant listing. Transplant units should engage in individualised risk-benefit discussions with patients, avoid the language of mandated treatments and strongly encourage uptake of the vaccine in all patient groups, using tailor-made educational initiatives.
随着 SARS-CoV-2 疫苗开始推出,移植单位面临的一个关键问题是,是否应将移植列入名单取决于接受者是否接种了疫苗。我们旨在为考虑拒绝接种疫苗的潜在移植候选人提供一个伦理框架。我们召集了一个由移植专业人员、非专业成员和患者组成的工作组,进行了文献回顾和共识过程。该工作组的工作还参考了两个医院临床伦理委员会的讨论。我们审查了在为肾移植进行名单登记之前接种疫苗的利弊,并考虑了与强制接种疫苗相关的一些实际困难。我们建议将疫苗接种状况作为与移植名单相关的 SARS-CoV-2 相关风险因素之一来考虑,而不是要求所有患者在移植前必须接种 SARS-CoV-2 疫苗。移植单位应与患者进行个体化的风险-效益讨论,避免使用强制治疗的语言,并通过量身定制的教育计划,在所有患者群体中大力鼓励接种疫苗。