Cox S W, Eley B M
Department of Periodontology, King's College Hospital Dental School, London, England, U.K.
Arch Oral Biol. 1987;32(4):257-63. doi: 10.1016/0003-9969(87)90019-7.
With both types of amalgam there was initial loss of material during healing of the implantation wounds. The rate of Hg release from the healed lesion was estimated by linear regression analysis of the content of implants when removed sequentially over 2 years. There were no significant differences between the amalgams, when expressed in absolute terms or as a percentage of the Hg content of the lesions immediately after healing, probably because gamma 1 (Ag2Hg3) phase breakdown was largely or solely responsible for Hg release with both materials. Hg levels in the blood, liver, renal cortex and faeces were all significantly lower with high-Cu amalgam which might be explained by the interference by Cu with Hg retention. There was no significant difference in urinary Hg excretion by the two groups of animals over the greater part of the study.
两种类型的汞合金在植入伤口愈合过程中均出现了材料的初始损失。通过对在两年内依次取出的植入物中的汞含量进行线性回归分析，估算了愈合损伤处汞的释放速率。以绝对含量或愈合后立即测量的损伤中汞含量的百分比来表示时，两种汞合金之间没有显著差异，这可能是因为γ1（Ag2Hg3）相分解在很大程度上或完全导致了两种材料的汞释放。高铜汞合金组动物血液、肝脏、肾皮质和粪便中的汞含量均显著较低，这可能是由于铜对汞潴留的干扰所致。在研究的大部分时间里，两组动物的尿汞排泄量没有显著差异。
