Institute of Organic Chemistry and Chemical Biology, Goethe-University Frankfurt, Max-von-Laue-Straße 9, Frankfurt am Main 60438, Germany.
Max Planck Institute for Brain Research, Max-von-Laue Str. 4, Frankfurt am Main 60438, Germany.
Chem Commun (Camb). 2021 Nov 25;57(94):12683-12686. doi: 10.1039/d1cc05664f.
Herein, we present a new class of Q-dye molecular beacons (MBs) that can be locally activated with visible light in hippocampal neurons. Our novel architecture increases the available monitoring time for neuronal mRNA from several minutes to 14 hours, since a lower light-sampling rate is required for tracking.
在此，我们提出了一类新的 Q-dye 分子信标 (MBs)，它们可以在海马神经元中用可见光局部激活。我们的新架构将神经元 mRNA 的可用监测时间从几分钟增加到 14 小时，因为跟踪所需的光采样率较低。
