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胸痛患者到急诊科就诊后行冠状动脉计算机断层扫描血管造影和负荷超声心动图检查后的资源利用情况

Resource Utilization Following Coronary Computed Tomographic Angiography and Stress Echocardiography in Patients Presenting to the Emergency Department With Chest Pain.

作者信息

Sturts Adam, Ruzieh Mohammed, Dhruva Sanket S, Peterson Brandon, Mandrola John M, Liu Guodong, Redberg Rita F, Foy Andrew J

机构信息

Department of Medicine, Penn State Milton S. Hershey Medical Center, Hershey, Pennsylvania.

Division of Cardiology, University of Florida Health Shands, Gainesville, Florida.

出版信息

Am J Cardiol. 2022 Jan 15;163:8-12. doi: 10.1016/j.amjcard.2021.09.043. Epub 2021 Nov 14.

Abstract

This study aimed to assess long-term resource utilization and outcomes in patients with acute chest pain who underwent coronary computed tomography angiography (CCTA) and stress echocardiography (SE). This was a retrospective, propensity-matched analysis of health insurance claims data for a national sample of privately insured patients over the period January 1, 2011, to December 31, 2014. There were 3,816 patients matched 1:1 who received either CCTA (n = 1,908) or SE (n = 1,908). Patients were seen in the emergency department (ED) between January 1, 2011, and December 31, 2011 with a primary diagnosis of chest pain and received either CCTA or SE within 72 hours as the first noninvasive test and maintained continuous enrollment in the database from the time of the ED encounter through December 31, 2014. All individual patient data were censored at 3 years. Compared with SE, CCTA was associated with higher odds of downstream cardiac catheterization (9.9% vs 7.7%, adjusted odds ratio [AOR] 1.28, 95% confidence interval (CI) 1.00 to 1.63), future noninvasive testing (27.7% vs 22.3%, AOR 1.22, 95% CI 1.05 to 1.42), and return ED visits or hospitalization for chest pain at 3 years (33.1% vs 24.2%, AOR 1.37, 95% CI 1.19 to 1.59). There were no statistically significant differences in new statin use (15.5% vs 14.9%, AOR 1.04, 95% CI 0.85 to 1.28), coronary revascularization (2.7% vs 2.2%, AOR 1.25, 95% CI 0.77 to 2.01) or hospitalization for acute myocardial infarction (0.9% vs 0.9%, AOR 0.96, 95% CI 0.47 to 1.99). In conclusion, in patients who present to the ED with chest pain, CCTA is associated with increased downstream resource utilization compared with SE with no differences in long-term cardiovascular outcomes.

摘要

本研究旨在评估接受冠状动脉计算机断层扫描血管造影(CCTA)和负荷超声心动图(SE)的急性胸痛患者的长期资源利用情况和结局。这是一项对2011年1月1日至2014年12月31日期间全国范围内私人保险患者的健康保险理赔数据进行的回顾性倾向匹配分析。共有3816例患者按1:1匹配,分别接受了CCTA(n = 1908)或SE(n = 1908)。患者于2011年1月1日至2011年12月31日期间在急诊科就诊,初步诊断为胸痛,并在72小时内接受了CCTA或SE作为首次无创检查,且从急诊科就诊时起至2014年12月31日在数据库中持续登记。所有个体患者数据在3年时进行审查。与SE相比,CCTA与下游心脏导管插入术的较高几率相关(9.9%对7.7%,调整优势比[AOR]1.28,95%置信区间[CI]1.00至1.63)、未来无创检查(27.7%对22.3%,AOR 1.22,95%CI 1.05至1.42)以及3年时因胸痛返回急诊科就诊或住院(33.1%对24.2%,AOR 1.37,95%CI 1.19至1.59)。在新使用他汀类药物(15.5%对14.9%,AOR 1.04,95%CI 0.85至1.28)、冠状动脉血运重建(2.7%对2.2%,AOR 1.25,95%CI 0.77至2.01)或急性心肌梗死住院(0.9%对0.9%,AOR 0.96,95%CI 0.47至1.99)方面无统计学显著差异。总之,对于因胸痛就诊于急诊科的患者,与SE相比,CCTA与下游资源利用增加相关,而长期心血管结局无差异。

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