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胸外科医生术前评估的手术风险与标准化手术风险预测工具的比较

Comparison of Preoperative Surgical Risk Estimated by Thoracic Surgeons vs a Standardized Surgical Risk Prediction Tool.

作者信息

Dyas Adam R, Colborn Kathryn L, Bronsert Michael R, Henderson William G, Mason Nicholas J, Rozeboom Paul D, Pradhan Nisha, Lambert-Kerzner Anne, Meguid Robert A

机构信息

Surgical Outcomes and Applied Research Program, Department of Surgery, University of Colorado School of Medicine, Aurora, Colorado.

Surgical Outcomes and Applied Research Program, Department of Surgery, University of Colorado School of Medicine, Aurora, Colorado; Department of Biostatistics and Informatics, Colorado School of Public Health, Aurora, Colorado.

出版信息

Semin Thorac Cardiovasc Surg. 2022 Winter;34(4):1378-1385. doi: 10.1053/j.semtcvs.2021.11.008. Epub 2021 Nov 13.

Abstract

Considerable variability exists between surgeons' assessments of a patient's individual preoperative surgical risk. Surgical risk calculators are not routinely used despite their validation. We sought to compare thoracic surgeons' prediction of patients' risk of postoperative adverse outcomes vs a surgical risk calculator, the Surgical Risk Preoperative Assessment System (SURPAS). We developed vignettes from 30 randomly selected patients who underwent thoracic surgery in the American College of Surgeons' National Surgical Quality Improvement Program database. Twelve thoracic surgeons estimated patients' preoperative risks of postoperative morbidity and mortality. These were compared to SURPAS estimates of the same vignettes. C-indices and Brier scores were calculated for the surgeons' and SURPAS estimates. Agreement between surgeon estimates was examined using intraclass correlation coefficients (ICCs). Surgeons estimated higher morbidity risk compared to SURPAS for low-risk patients (ASA classes 1-2, 11.5% vs 5.1%, P ≤ 0.001) and lower morbidity risk compared to SURPAS for high-risk patients (ASA class 5, 37.6% vs 69.8%, P < 0.001). This trend also occurred in high-risk patients for mortality (ASA 5, 11.1% vs 44.3%, P < 0.001). C-indices for SURPAS vs surgeons were 0.84 vs 0.76 (P = 0.3) for morbidity and 0.98 vs 0.85 (P = 0.001) for mortality. Brier scores for SURPAS vs surgeons were 0.1579 vs 0.1986 for morbidity (P = 0.03) and 0.0409 vs 0.0543 for mortality (P = 0.006). ICCs showed that surgeons had moderate risk agreement for morbidity (ICC = 0.654) and mortality (ICC = 0.507). Thoracic surgeons and patients could benefit from using a surgical risk calculator to better estimate patients' surgical risks during the informed consent process.

摘要

外科医生对患者个体术前手术风险的评估存在很大差异。尽管手术风险计算器已经得到验证,但并未常规使用。我们试图比较胸外科医生对患者术后不良结局风险的预测与一种手术风险计算器——手术风险术前评估系统(SURPAS)。我们从美国外科医师学会国家外科质量改进计划数据库中随机选取了30例接受胸外科手术的患者编写病例 vignettes。12名胸外科医生估计了患者术前术后发病和死亡的风险。将这些估计值与SURPAS对相同病例 vignettes 的估计值进行比较。计算了外科医生和SURPAS估计值的C指数和Brier分数。使用组内相关系数(ICC)检查外科医生估计值之间的一致性。对于低风险患者(美国麻醉医师协会分级1 - 2级),外科医生估计的发病风险高于SURPAS(11.5%对5.1%,P≤0.001);对于高风险患者(美国麻醉医师协会分级5级),外科医生估计的发病风险低于SURPAS(37.6%对69.8%,P<0.001)。这种趋势在高风险患者的死亡风险估计中也出现了(美国麻醉医师协会分级5级,11.1%对44.3%,P<0.001)。SURPAS与外科医生的发病风险C指数分别为0.84和0.76(P = 0.3),死亡风险C指数分别为0.98和0.85(P = 0.001)。SURPAS与外科医生的发病风险Brier分数分别为0.1579和0.1986(P = 0.03),死亡风险Brier分数分别为0.0409和0.0543(P = 0.006)。ICC显示,外科医生在发病风险(ICC = 0.654)和死亡风险(ICC = 0.507)方面有中等程度的风险一致性。胸外科医生和患者可以通过使用手术风险计算器在知情同意过程中更好地估计患者的手术风险而受益。

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