Lee Dae Hyun, Patel Raj H, Mehra Ishita, Shenoy Rahul, Nanjappa Sowmya, Greene John
Cardiology, University of South Florida, Tampa, USA.
Internal Medicine, Edward Via College of Osteopathic Medicine, Monroe, USA.
Cureus. 2021 Oct 9;13(10):e18627. doi: 10.7759/cureus.18627. eCollection 2021 Oct.
( ) is a ubiquitous microorganism previously known as It is emerging as a pathogen responsible for bacteremia in the immunocompromised population, particularly in cancer patients and those with a history of prolonged hospital stay and frequent instrumentations. A retrospective chart review of all cases over 10 years at the Moffitt Cancer Center showed a total of three patients with infection. The first patient (history of multiple myeloma) underwent endoscopy complicated by aspiration pneumonia and positive blood culture for infection. The second patient (current acute myelogenous leukemia) had neutropenic fever in the setting of a recent chest port infection. Blood culture from the chest port showed . The third patient (history of esophageal adenocarcinoma and acute myelogenous leukemia) had a history of recent pneumonia and cellulitis who presented with recurrent neutropenic fever. Blood culture was positive for . bacteremia has a high 28-day mortality rate (41%). As these three cases illustrate, early identification of the pathogen along with empiric treatment with a fluoroquinolone and/or minocycline is indicated to reduce morbidity and mortality.
（ ）是一种普遍存在的微生物，以前称为 。它正逐渐成为免疫功能低下人群菌血症的病原体，尤其是癌症患者以及有长期住院和频繁接受器械检查病史的患者。对莫菲特癌症中心10年以上的所有病例进行的回顾性图表审查显示，共有3例 感染患者。首例患者（多发性骨髓瘤病史）接受内镜检查，并发吸入性肺炎，血培养 感染呈阳性。第二例患者（目前患有急性髓系白血病）在近期胸部端口感染的情况下出现中性粒细胞减少性发热。胸部端口的血培养显示 。第三例患者（食管腺癌和急性髓系白血病病史）近期有肺炎和蜂窝织炎病史，出现复发性中性粒细胞减少性发热。血培养 呈阳性。 菌血症的28天死亡率很高（41%）。正如这三个病例所示，为降低发病率和死亡率，需要早期识别病原体并使用氟喹诺酮类和/或米诺环素进行经验性治疗。
