Gorgani Farzan M, Beyer Todd L
Novus Total Eye Care, 518 West Ave, Tallmadge, OH, USA.
Cleveland Clinic Akron General, 1 Akron General Ave, Akron, OH, USA.
Am J Ophthalmol Case Rep. 2021 Nov 4;24:101220. doi: 10.1016/j.ajoc.2021.101220. eCollection 2021 Dec.
To present to and inform the practitioner of an unusual presentation of Varicella zoster virus and Ramsay-Hunt Syndrome.
A 69-year-old bedbound male with vascular dementia presented to the emergency room with a red right eye with associated tearing and mucus production. The patient could not express if he was in pain. The initial diagnosis from the emergency room was bacterial keratitis, confirmed with a positive pseudomonas culture. However, upon examination by the ophthalmologist it was noted that there was not only a large, infected epithelial defect, but also an intraocular pressure of 35 and a candy-cane hypopyon. The diagnosis of herpes neurotrophic keratitis and iridocyclitis was made and the patient was started on intravenous acyclovir along with the appropriate topical medications. A day later, it was noted that the patient developed a right sided facial palsy and vesicular lesions inside the right ear canal, as confirmed by otolaryngology.
Ramsay-Hunt Syndrome is usually known to the ophthalmologist due to the exposure keratopathy caused by facial palsy. This case demonstrates varicella-zoster virus (VZV) neurotrophic keratitis preceding the development of facial palsy, which can further exacerbate an already neurotrophic cornea. The practitioner should be aware of these signs and symptoms and adjust their treatment with systemic acyclovir-prednisone.
向从业者介绍并告知水痘带状疱疹病毒和拉姆齐-亨特综合征的一种不寻常表现。
一名69岁的卧床男性,患有血管性痴呆,因右眼发红伴流泪和产生黏液而被送往急诊室。患者无法表达自己是否疼痛。急诊室的初步诊断为细菌性角膜炎,假单胞菌培养呈阳性得以证实。然而,眼科医生检查时发现,不仅存在一个大的感染性上皮缺损,而且眼压为35,还有“糖果棒”样前房积脓。诊断为疱疹性神经营养性角膜炎和虹膜睫状体炎,患者开始接受静脉注射阿昔洛韦以及适当的局部用药。一天后,耳鼻喉科检查证实患者出现右侧面瘫和右耳道内的水疱性病变。
由于面瘫引起的暴露性角膜病变,眼科医生通常了解拉姆齐-亨特综合征。该病例显示,在面瘫发生之前出现了水痘带状疱疹病毒(VZV)神经营养性角膜炎,这会进一步加重已经存在的神经营养性角膜病变。从业者应了解这些体征和症状,并调整全身使用阿昔洛韦-泼尼松的治疗方案。