Yang Rui, Lu Zhenqi, Gu Xiaofeng, Dai Bo
Department of Nursing, Fudan University Shanghai Cancer Center, Shanghai, China.
Department of Oncology, Shanghai Medical College, Fudan University, Shanghai, China.
Asia Pac J Oncol Nurs. 2021 Oct 4;8(6):639-652. doi: 10.4103/apjon.apjon-2138. eCollection 2021 Nov-Dec.
This study was conducted to evaluate the effect of an information support program on the self-efficacy (SE) of prostate cancer (PCa) patients receiving hormonal therapy (HT).
Based on the information support program constructed in a previous study, a randomized controlled trial was conducted in a cancer hospital in Shanghai, China. One hundred subjects were randomly divided into two groups. The control group was provided routine care and communication, and the experimental group participated in an informational support program. Three months later, the following outcomes were compared between the two groups: information acquisition, disease knowledge mastery, SE, healthy behavior adherence, health-related quality of life (HRQoL), and serum prostate-specific antigen (PSA) levels. -test and Wilcoxon rank-sum test were used to compare the differences between the two groups, and intention-to-treat analysis was used to increase the reliability of the results.
After the intervention, information acquisition, disease knowledge mastery, and the SE and healthy behavior adherence of the experimental group were significantly increased compared with the control group, whereas the HRQoL and PSA did not significantly differ from that observed in the control group.
The results showed that information support programs improve information acquisition, disease knowledge mastery, SE, and healthy behavior adherence among PCa patients receiving HT.
本研究旨在评估信息支持项目对接受激素治疗（HT）的前列腺癌（PCa）患者自我效能（SE）的影响。
基于先前研究构建的信息支持项目，在中国上海的一家癌症医院进行了一项随机对照试验。100名受试者被随机分为两组。对照组接受常规护理和沟通，实验组参与信息支持项目。三个月后，比较两组的以下结果：信息获取、疾病知识掌握、自我效能、健康行为依从性、健康相关生活质量（HRQoL）和血清前列腺特异性抗原（PSA）水平。采用t检验和Wilcoxon秩和检验比较两组间差异，并采用意向性分析以提高结果的可靠性。
干预后，实验组的信息获取、疾病知识掌握、自我效能和健康行为依从性与对照组相比显著提高，而健康相关生活质量和PSA与对照组相比无显著差异。
结果表明，信息支持项目可改善接受HT的PCa患者的信息获取、疾病知识掌握、自我效能和健康行为依从性。
