Hemmer K M, McAlister W H, Marsh J L
Washington University Medical Center, St. Louis, MO.
Cleft Palate J. 1987 Oct;24(4):328-33.
Cervical spine radiographs of 34 patients with a variety of craniosynostosis syndromes were reviewed to determine the incidence and nature of skeletal anomalies and to evaluate the findings in terms of syndromal patterns. Intervertebral fusions occurred in 30 percent of Pfeiffer's, 38 percent of Crouzon's, and 71 percent of Apert's syndrome children. In Crouzon's and Pfeiffer's syndromes, isolated upper cervical fusions were most common; in Apert's syndrome, the fusions were more likely to be complex involving C5-C6. This syndromal variation, however, was not specific enough for diagnostic differentiation.
回顾了34例患有各种颅缝早闭综合征患者的颈椎X光片，以确定骨骼异常的发生率和性质，并根据综合征模式评估检查结果。在患有Pfeiffer综合征的儿童中，30%发生了椎间融合；在患有Crouzon综合征的儿童中，这一比例为38%；而在患有Apert综合征的儿童中，这一比例为71%。在Crouzon综合征和Pfeiffer综合征中，孤立的上颈椎融合最为常见；在Apert综合征中，融合更可能是复杂的，累及C5-C6。然而，这种综合征差异对于诊断鉴别来说特异性不足。
