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儿童新发感染的预防。

Prevention of Emerging Infections in Children.

机构信息

Division of Pediatric Infectious Diseases, Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, King Chulalongkorn Memorial Hospital, 9th Floor, Sor Kor Building, Rama 4 Road, Patumwan, Bangkok 10330, Thailand.

Department of Pediatrics, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.

出版信息

Pediatr Clin North Am. 2022 Feb;69(1):185-202. doi: 10.1016/j.pcl.2021.08.006.

Abstract

Prevention of emerging infections in children is a dynamic arena where substantial medical advances have enabled intervention and prevention of infection outbreaks. This article discusses 5 infections causing significant morbidity and mortality across Asia, Latin America, and Africa. Avian influenza and the Middle East respiratory syndrome are highly contagious zoonoses spread through aerosol and droplets, affecting predominantly Asia. Dengue infection and chikungunya are endemic mosquito-borne viruses in tropical regions across Asia, Latin America, and Africa. Ebola is a highly contagious virus spread through human-to-human contact. The latest information in clinical manifestations, infection, prevention control, chemoprophylaxis, vaccination, and public health measures is reviewed.

摘要

预防儿童新发传染病是一个充满活力的领域,医学的重大进步使我们能够干预和预防感染的爆发。本文讨论了在亚洲、拉丁美洲和非洲导致发病率和死亡率高的 5 种传染病。禽流感和中东呼吸综合征是通过气溶胶和飞沫传播的高度传染性人畜共患病,主要影响亚洲。登革热和基孔肯雅热是亚洲、拉丁美洲和非洲热带地区流行的蚊媒病毒。埃博拉病毒是一种通过人与人之间的接触传播的高传染性病毒。本文回顾了这些传染病的最新临床表现、感染、防控、化学预防、疫苗接种和公共卫生措施等方面的信息。

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本文引用的文献

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Adenoviral Vectors as Vaccines for Emerging Avian Influenza Viruses.腺病毒载体作为新兴禽流感病毒疫苗。
Front Immunol. 2021 Jan 29;11:607333. doi: 10.3389/fimmu.2020.607333. eCollection 2020.
4
Dengue vaccine development by the year 2020: challenges and prospects.2020 年登革热疫苗的开发:挑战与展望。
Curr Opin Virol. 2020 Aug;43:71-78. doi: 10.1016/j.coviro.2020.09.004. Epub 2020 Oct 18.
5
Dengue vaccine: a key for prevention.登革热疫苗:预防的关键。
Expert Rev Vaccines. 2020 Jun;19(6):499-506. doi: 10.1080/14760584.2020.1775076. Epub 2020 Jun 16.

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