Department of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan; Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan.
Institute of Clinical Medicine, National Yang-Ming University, Taipei, Taiwan; Department of Pathology and Laboratory Medicine, Taipei Veterans General Hospital, Taiwan.
Taiwan J Obstet Gynecol. 2021 Nov;60(6):1116-1120. doi: 10.1016/j.tjog.2021.09.028.
Adult-type granulosa cell tumors (GCT) are sex cord-stromal tumors and often accompanied with abdominal distention and hyperestrogenism-related symptoms. Adult-type GCT-presenting ascites and pleural effusion is extremely rare.
A 56-year-old perimenopausal woman presented with abdominal distention and abnormal vaginal spotting. Ultrasound and abdominal computed tomography showed a complex cystic mass in the left ovary accompanied with bilateral pleural effusion and ascites. The patient underwent total abdominal hysterectomy, bilateral salpingo-oophorectomy, left pelvic lymph node dissection, omentectomy and appendectomy. Final histopathological diagnosis was adult-type GCT. The patient had postoperative hormone and anti-angiogenesis agent therapy with free of disease.
Ovarian cystic complex mass accompanied with ascites and pleural effusion often results from malignant ovarian tumors or benign ovarian fibroma. Based on the aforementioned report, the rare types of ovarian tumors, such as adult-type granulosa cell tumor of the ovary should be taken into consideration.
成人型颗粒细胞瘤（GCT）属于性索-间质肿瘤，常伴有腹胀和雌激素相关症状。成人型 GCT 合并腹水和胸腔积液极为罕见。
一名 56 岁围绝经期女性因腹胀和阴道异常出血就诊。超声和腹部 CT 显示左侧卵巢有一个复杂的囊性肿块，同时伴有双侧胸腔积液和腹水。患者接受了全子宫切除术、双侧输卵管卵巢切除术、左盆腔淋巴结清扫术、网膜切除术和阑尾切除术。最终的组织病理学诊断为成人型 GCT。患者术后接受激素和抗血管生成药物治疗，无疾病进展。
伴有腹水和胸腔积液的卵巢囊性复杂肿块通常是由恶性卵巢肿瘤或良性卵巢纤维瘤引起的。基于上述报告，应考虑罕见类型的卵巢肿瘤，如卵巢成人型颗粒细胞瘤。
