Core Facility Digital Medicine and Interoperability, Berlin Institute of Health at Charité -Universitätsmedizin Berlin, Germany.
Institute of Medical Informatics, Charité - Universitätsmedizin Berlin, Germany.
Stud Health Technol Inform. 2021 Nov 18;287:73-77. doi: 10.3233/SHTI210817.
Adopting international standards within health research communities can elevate data FAIRness and widen analysis possibilities. The purpose of this study was to evaluate the mapping feasibility against HL7® Fast Healthcare Interoperability Resources® (FHIR)® of a generic metadata schema (MDS) created for a central search hub gathering COVID-19 health research (studies, questionnaires, documents = MDS resource types). Mapping results were rated by calculating the percentage of FHIR coverage. Among 86 items to map, total mapping coverage was 94%: 50 (58%) of the items were available as standard resources in FHIR and 31 (36%) could be mapped using extensions. Five items (6%) could not be mapped to FHIR. Analyzing each MDS resource type, there was a total mapping coverage of 93% for studies and 95% for questionnaires and documents, with 61% of the MDS items available as standard resources in FHIR for studies, 57% for questionnaires and 52% for documents. Extensions in studies, questionnaires and documents were used in 32%, 38% and 43% of items, respectively. This work shows that FHIR can be used as a standardized format in registries for clinical, epidemiological and public health research. However, further adjustments to the initial MDS are recommended - and two additional items even needed when implementing FHIR. Developing a MDS based on the FHIR standard could be a future approach to reduce data ambiguity and foster interoperability.
在健康研究社区中采用国际标准可以提高数据的 FAIR 程度并拓宽分析可能性。本研究旨在评估针对 COVID-19 健康研究（研究、问卷、文档= MDS 资源类型）中央搜索中心创建的通用元数据架构 (MDS) 与 HL7® Fast Healthcare Interoperability Resources® (FHIR)® 的映射可行性。映射结果通过计算 FHIR 覆盖率的百分比进行评分。在 86 个要映射的项目中，总映射覆盖率为 94%：50 个（58%）项目可作为 FHIR 中的标准资源，31 个（36%）可以使用扩展映射。有 5 个项目（6%）无法映射到 FHIR。分析每个 MDS 资源类型，研究的总映射覆盖率为 93%，问卷和文档的总映射覆盖率为 95%，研究的 MDS 项目中有 61%可作为 FHIR 中的标准资源，问卷中有 57%，文档中有 52%。研究、问卷和文档中的扩展分别在 32%、38%和 43%的项目中使用。这项工作表明，FHIR 可以用作临床、流行病学和公共卫生研究登记处的标准化格式。但是，建议对初始 MDS 进行进一步调整——在实施 FHIR 时甚至需要另外两个项目。基于 FHIR 标准开发 MDS 可能是减少数据歧义并促进互操作性的未来方法。
