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在埃塞俄比亚 MaddaWalabu 大学 Goba 转诊医院住院的患者中的细菌谱及其抗菌药物敏感性模式:一项横断面研究。

Bacterial profile and their antimicrobial susceptibility patterns in patients admitted at MaddaWalabu University Goba Referral Hospital, Ethiopia: a cross sectional study.

机构信息

Department of Medical Laboratory Sciences, MaddaWalabu University, Ethiopia.

Department of Medical Laboratory Sciences, Wolaita Sodo University, Ethiopia.

出版信息

Afr Health Sci. 2021 Jun;21(2):513-522. doi: 10.4314/ahs.v21i2.5.

Abstract

BACKGROUND

Hospital acquired infections (HAIs) are one of the global concerns in resource limited settings. The aim of the study was to determine bacteria profile and their antimicrobial susceptibility patterns among patients admitted at surgical and medical wards.

METHODS

A hospital based cross-sectional study was conducted from November 2016 to July 2017 in MaddaWalabu University Goba Referral Hospital. Urine and wound swabs were processed and standard disk diffusion test was done to assess susceptibility pattern. Association among variables was determined by Chi-square test.

RESULTS

Among 207 patients enrolled, 24.6% developed HAI, of which, 62.7% and 37.3% were from surgical and medical wards, respectively. The male to female ratio was 1.5:1. The age ranged from 19 to 74 years with a mean of 41.65(±16.48) years. A total 62 bacteria were isolated in which majority of the isolates were gram negative bacteria. Most isolates were resistance to most of the antibiotics tested but sensitive to Ceftriaxone, Norfloxacin and Ciprofloxacin.

CONCLUSION

Due to the presence of high level drug resistant bacteria, empirical treatment to HAI may not be effective. Therefore, treatment should be based on the result of culture and sensitivity.

摘要

背景

医院获得性感染(HAIs)是资源有限环境中的全球关注问题之一。本研究旨在确定外科和内科病房住院患者的细菌谱及其抗菌药物敏感性模式。

方法

本研究是 2016 年 11 月至 2017 年 7 月在马达加斯加戈巴转诊医院进行的一项基于医院的横断面研究。对尿液和伤口拭子进行处理,并进行标准圆盘扩散试验以评估药敏模式。通过卡方检验确定变量之间的关联。

结果

在纳入的 207 名患者中,24.6%发生了 HAI,其中 62.7%和 37.3%分别来自外科和内科病房。男女比例为 1.5:1。年龄从 19 岁到 74 岁,平均年龄为 41.65(±16.48)岁。共分离出 62 株细菌,其中大多数为革兰氏阴性菌。大多数分离株对大多数测试的抗生素具有耐药性,但对头孢曲松、诺氟沙星和环丙沙星敏感。

结论

由于存在高水平耐药菌,针对 HAI 的经验性治疗可能无效。因此,治疗应基于培养和药敏结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/eb1b/8568252/cb66916eecc6/AFHS2102-0513Fig1.jpg

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