National Center for Chronic and Noncommunicable Disease Control and Prevention, Chinese Center for Disease Control and Prevention, Beijing, China.
Hubei Provincial Center for Disease Control and Prevention, Wuhan, China.
Front Public Health. 2021 Nov 2;9:733314. doi: 10.3389/fpubh.2021.733314. eCollection 2021.
This study aims to estimate the prevalence of dementia and Alzheimer's disease (AD) and associated risk factors among the general Chinese population. We carried out a nationwide study including 24,117 participants aged 60 years and older in China using a multistage clustered sampling. Dementia and AD were diagnosed according to the fourth edition of the Diagnostic and Statistical Manual of Mental Disorders and the criteria issued by the National Institute of Neurological and Communicative Disorders and Stroke-Alzheimer's Disease and Related Disorders Association. Face-to-face interviews were administered by the trained interviewers to obtain information on demographics, lifestyle factors, and previous diseases. The overall weighted prevalence of dementia was 4.22% (95%CI 2.27-6.17%) for people aged 60 years and older, was higher in women than in men and increased with age. Daily tea drinking and daily exercises were the protective factors for both dementia and AD. Engaging in social and intellectual activities was significantly associated with a lower risk of dementia and AD. A large number of population with dementia posed a significant challenge to China where the population is rapidly aging. The increase of public awareness, building more care facilities, and training dementia specialists and professional caregivers are all urgently needed and should be the future priorities of dementia care in China.
本研究旨在估计中国一般人群中痴呆症和阿尔茨海默病(AD)的患病率及相关危险因素。我们在中国进行了一项全国性研究,纳入了 24117 名年龄在 60 岁及以上的参与者,采用多阶段聚类抽样方法。根据《精神障碍诊断与统计手册》第四版和美国国立神经病学、语言障碍和卒中-阿尔茨海默病及相关疾病协会发布的标准,对痴呆症和 AD 进行诊断。由经过培训的调查员进行面对面访谈,以获取人口统计学、生活方式因素和既往疾病的信息。60 岁及以上人群痴呆症的总加权患病率为 4.22%(95%CI 2.27-6.17%),女性高于男性,且随年龄增长而增加。每日饮茶和每日锻炼是痴呆症和 AD 的保护因素。参与社会和智力活动与痴呆症和 AD 的风险降低显著相关。大量的痴呆症患者给中国带来了巨大的挑战,中国的人口正在迅速老龄化。提高公众意识、建立更多的护理设施、培训痴呆症专家和专业护理人员都是迫切需要的,应该成为中国痴呆症护理的未来重点。