Yang Lu, Wang Bingren, Yin Xianjie, Zeng Qingle
Key Laboratory of General Chemistry of the National Ethnic Affairs Commission, School of Chemistry and Environment, Southwest Minzu University, Chengdu, 610041, China.
State Key Laboratory of Geohazard Prevention and Geoenvironment Protection, College of Materials, Chemistry and Chemical Engineering, Chengdu University of Technology, Chengdu, 610059, China.
Chem Rec. 2022 Mar;22(3):e202100242. doi: 10.1002/tcr.202100242. Epub 2021 Nov 18.
In recent years, sulfenate anions as key intermediates in enantioselective synthesis have attracted considerable attention. Typically, development of novel synthetic methods to generate sulfenate anions allows for the preparation of various enantiopure sulfoxides, which are prevalently used as auxiliaries, ligands, organocatalysts, and biologically active compounds. This review presents the in situ preparation methods and the recent applications of sulfenate anions in catalytic asymmetric synthesis of chiral sulfoxides.
近年来，亚磺酸盐阴离子作为对映选择性合成中的关键中间体受到了广泛关注。通常，开发生成亚磺酸盐阴离子的新型合成方法能够制备各种对映体纯的亚砜，这些亚砜广泛用作助剂、配体、有机催化剂和生物活性化合物。本文综述了亚磺酸盐阴离子在手性亚砜催化不对称合成中的原位制备方法及近期应用。
