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微藻中生物活性化合物在医药和化妆品方面的应用进展。

Application progress of bioactive compounds in microalgae on pharmaceutical and cosmetics.

机构信息

Institute of Biological Sciences, Faculty of Science, Universiti Malaya, 50603, Kuala Lumpur, Malaysia.

College of Chemistry and Chemical Engineering, Xiamen University, Xiamen, 361005, Fujian, China.

出版信息

Chemosphere. 2022 Mar;291(Pt 2):132932. doi: 10.1016/j.chemosphere.2021.132932. Epub 2021 Nov 16.

Abstract

Microalgae is an autotrophic organism with fast growth, short reproduction cycle, and strong environmental adaptability. In recent years, microalgae and the bioactive ingredients extracted from microalgae are regarded as potential substitutes for raw materials in the pharmaceutical and the cosmetics industry. In this review, the characteristics and efficacy of the high-value components of microalgae are discussed in detail, along with the sources and extraction technologies of algae used to obtain high-value ingredients are reviewed. Moreover, the latest trends in biotherapy based on high-value algae extracts as materials are discussed. The excellent antioxidant properties of microalgae derivatives are regarded as an attractive replacement for safe and environmentally friendly cosmetics formulation and production. Through further studies, the mechanism of microalgae bioactive compounds can be understood better and reasonable clinical trials conducted can safely conclude the compliance of microalgae-derived drugs or cosmetics to be necessary standards to be marketed.

摘要

微藻是一种具有快速生长、短繁殖周期和强环境适应性的自养生物。近年来,微藻及其提取的生物活性成分被视为医药和化妆品行业原料的潜在替代品。本文详细讨论了微藻的高价值成分的特性和功效,以及从藻类中提取高价值成分的来源和提取技术。此外,还讨论了基于高价值藻类提取物作为材料的生物治疗的最新趋势。微藻衍生物具有出色的抗氧化性能,被认为是安全环保的化妆品配方和生产的有吸引力的替代品。通过进一步研究,可以更好地了解微藻生物活性化合物的作用机制,并进行合理的临床试验,以安全地确定符合微藻衍生药物或化妆品的必要标准,从而推向市场。

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