Ohba T, Suzuki T, Watanabe C, Himeno S
Department of Human Ecology, School of Health Sciences, Faculty of Medicine, University of Tokyo, Japan.
Toxicol Lett. 1987 Dec;39(2-3):275-81. doi: 10.1016/0378-4274(87)90243-8.
Injection (s.c.) of Na2SeO3 (SS, 20-30 mumol/kg) into male mice initiated eating, which began about 20 min after injection and continued for about 3 h. This initiation effect was observed for mice of different ages and at different times of the day. Other findings of this study were: (1) early morning injection (30 mumol/kg) caused increased food intake, as examined by gastric content 3 h after injection, compared to daytime injection; and (2) SS-induced transient hyperphagia was observed at ambient temperatures of 10 and 22 degrees C, but not at 37 degrees C. This paper discusses these results in relation to SS-induced hypothermia.
给雄性小鼠皮下注射亚硒酸钠（SS，20 - 30 μmol/kg）会引发进食行为，该行为在注射后约20分钟开始，并持续约3小时。不同年龄的小鼠以及一天中的不同时间均观察到这种引发效应。本研究的其他发现如下：（1）与白天注射相比，清晨注射（30 μmol/kg）后3小时通过胃内容物检测发现食物摄入量增加；（2）在10℃和22℃的环境温度下观察到SS诱导的短暂食欲亢进，但在37℃时未观察到。本文讨论了这些结果与SS诱导的体温过低的关系。
