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[上睑下垂的治疗]

[Management of ptosis].

作者信息

Martel A

机构信息

Service d'ophtalmologie, CHU de Nice, université Nice Cote-d'Azur, hôpital Pasteur 2, 30, voie Romaine, 06000 Nice, France.

出版信息

J Fr Ophtalmol. 2022 Feb;45(2):233-246. doi: 10.1016/j.jfo.2021.09.005. Epub 2021 Nov 17.

Abstract

Ptosis is defined as a drooping of the upper eyelid. It often results in functional and/or aesthetic impairment. Although often benign, ptosis may be the first symptom of a life-threatening condition (carotid dissection, intracranial aneurism, generalized myasthenia). Only a rigorous, systematic and clinical examination will allow the physician to distinguish "benign ptosis" from "urgent ptosis". The history should attempt to detect a daily variation in the ptosis, suggesting myasthenia gravis. Pupillary examination should rule out myosis, which would suggest Claude Bernard-Horner's syndrome (secondary to an internal carotid dissection until proven otherwise), or mydriasis, suggesting an intracranial aneurism. Once an emergency has been ruled out, the clinical examination should assess the levator muscle strength (helpful for determining the underlying etiology) and the Bell's phenomenon (the lack of which is predictive of postoperative corneal exposure). The amount of ptosis is not related to its etiology. At the conclusion of the examination, the physician must be able to classify the ptosis as either pseudoptosis, aponeurotic ptosis, neurogenic ptosis, myogenic ptosis, or junctional ptosis (myasthenia). Except for "urgent ptosis", requiring multidisciplinary medical treatment, surgery is the mainstay of treatment. The surgical technique is based on the etiology of the ptosis, the strength of the levator muscle and the phenylephrine test.

摘要

上睑下垂定义为上眼睑下垂。它常导致功能和/或美观受损。虽然上睑下垂通常为良性,但可能是危及生命状况(颈动脉夹层、颅内动脉瘤、全身性重症肌无力)的首发症状。只有通过严格、系统的临床检查,医生才能区分“良性上睑下垂”和“紧急上睑下垂”。病史应试图发现上睑下垂的每日变化,提示重症肌无力。瞳孔检查应排除瞳孔缩小(提示克劳德·伯纳德 - 霍纳综合征,继发于颈内动脉夹层,除非另有证实)或瞳孔散大(提示颅内动脉瘤)。一旦排除紧急情况,临床检查应评估提上睑肌力量(有助于确定潜在病因)和贝尔现象(缺乏该现象提示术后角膜暴露)。上睑下垂的程度与其病因无关。检查结束时,医生必须能够将上睑下垂分类为假性上睑下垂、腱膜性上睑下垂、神经源性上睑下垂、肌源性上睑下垂或交界性上睑下垂(重症肌无力)。除了需要多学科治疗的“紧急上睑下垂”外,手术是主要治疗方法。手术技术基于上睑下垂的病因、提上睑肌力量和苯肾上腺素试验。

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