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COVID-19 疫苗接种和癌症免疫疗法:它们应该结合在一起吗?

COVID-19 vaccination and cancer immunotherapy: should they stick together?

机构信息

Université Côte d'Azur, CNRS, Inserm, IRCAN, Centre Antoine Lacassagne, FHU-OncoAge, 06189, Nice, France.

Université Côte d'Azur, Laboratory of Clinical and Experimental Pathology, CHU-Nice, FHU OncoAge, Hospital-Integrated Biobank (BB-0033-00025), Nice, France.

出版信息

Br J Cancer. 2022 Jan;126(1):1-3. doi: 10.1038/s41416-021-01618-0. Epub 2021 Nov 19.

Abstract

The combination of COVID-19 vaccination with immunotherapy by checkpoint inhibitors in cancer patients could intensify immunological stimulation with potential reciprocal benefits. Here, we examine more closely the possible adverse events that can arise in each treatment modality. Our conclusion is that caution should be exercised when combining both treatments.

摘要

在癌症患者中,将 COVID-19 疫苗接种与免疫检查点抑制剂的免疫疗法相结合,可能会增强免疫刺激作用,并带来潜在的互惠益处。在这里,我们更仔细地研究了每种治疗方式可能出现的不良反应。我们的结论是,在联合使用这两种治疗方法时应谨慎行事。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/76c4/8727617/95c6139a86c6/41416_2021_1618_Fig1_HTML.jpg

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