Wolpaw J R, Lee C L
Wadsworth Center for Laboratories and Research, New York State Department of Health, Albany 12201.
Exp Brain Res. 1987;68(2):428-33. doi: 10.1007/BF00248809.
In preparation for studying the spinal cord alterations produced by operant conditioning of spinal reflexes, we studied peripheral nerve responses to supramaximal dorsal root stimulation in the lumbosacral cord of deeply anesthetized monkeys before and after thoracic cord transection. Except for variable depression in the first few minutes, reflex responses were not reduced or otherwise significantly affected by transection in the hour immediately following the lesion or for at least 50 h. The results suggest that reduction in muscle spindle sensitivity and/or in polysynaptic motoneuron excitation contributes to stretch reflex depression after cord transection.
为了准备研究脊髓反射操作性条件作用所产生的脊髓改变，我们在胸段脊髓横断前后，研究了深度麻醉的猴子腰骶段脊髓对背根最大刺激的外周神经反应。除了最初几分钟有不同程度的抑制外，在损伤后的即刻一小时内或至少50小时内，反射反应并未因横断而降低或受到其他显著影响。结果表明，肌梭敏感性降低和/或多突触运动神经元兴奋性降低是脊髓横断后牵张反射抑制的原因。
