人骨髓成纤维细胞的胶原蛋白合成
Collagen synthesis by human bone marrow fibroblasts.
作者信息
Fernández M, Minguell J J
机构信息
Unidad de Biologia Celular, Universidad de Chile, Santiago.
出版信息
Experientia. 1987 Dec 1;43(11-12):1223-5. doi: 10.1007/BF01945534.
PMID:3480234
Abstract
Collagen synthesis was measured in fibroblast cultures derived from normal and acute lymphoblastic leukemia (ALL) bone marrow. Collagen production was higher in normal than in ALL fibroblasts. These cells elaborate type I and type III procollagens in a ratio that depends on cell density and whether cells originate from normal or ALL bone marrow.
摘要
在源自正常和急性淋巴细胞白血病（ALL）骨髓的成纤维细胞培养物中测量胶原蛋白合成。正常成纤维细胞中的胶原蛋白产量高于ALL成纤维细胞。这些细胞以取决于细胞密度以及细胞源自正常骨髓还是ALL骨髓的比例合成I型和III型前胶原蛋白。
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