Department of Obstetrics and Gynecology, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, Jiangsu, China.
Departments of Laboratory Medicine, Nanjing Drum Tower Hospital, Nanjing University Medical School, Nanjing, Jiangsu, China.
Hum Vaccin Immunother. 2021 Dec 2;17(12):4946-4953. doi: 10.1080/21645515.2021.1997297. Epub 2021 Nov 22.
Before the availability of COVID-19 vaccines, surveys showed that vaccine hesitancy may influence the acceptance of COVID-19 vaccination. In this cross-sectional study, we aimed to investigate COVID-19 vaccination coverage among healthcare workers (HCWs) in obstetrics and gynecology, during the first three-month period of the vaccination campaign after COVID-19 vaccines were approved. A total of 662 eligible HCWs, consisting of 250 HCWs (group one) who participated in a Jiangsu provincial symposium and 412 HCWs (group two) in the department of obstetrics and gynecology, Nanjing Drum Tower Hospital, were invited to answer a 23-question questionnaire. In total, 618 (93.4%) HCWs completed the questionnaire. The vaccine acceptance in group one was higher than that in group two (87.2% [197/226] vs 74.2% [291/392], χ = 14.436, < .001). Overall, 488 (79.0%) HCWs received COVID-19 vaccination and 130 (21.0%) declined vaccination. One-third of the 488 vaccinees were not vaccinated until consulted with others or requested by employers. Adjusted logistic regression analysis showed that the decline of vaccination was associated with worry about the safety of the vaccine (OR 1.920, CI 95% 1.196-3.082; = .007). The main reason for the decline of COVID-19 vaccination included the concern about vaccine safety, pregnancy preparation, pregnancy, or lactation. These results indicate that more safety data about COVID-19 vaccines, particularly in pregnant or lactating women, are required to promote the acceptance of COVID-19 vaccination. In addition, vaccination requests or mandates by employers may increase the acceptance of COVID-19 vaccines.
在 COVID-19 疫苗可用之前,调查显示疫苗犹豫可能会影响 COVID-19 疫苗的接种接受率。在这项横断面研究中,我们旨在调查 COVID-19 疫苗获批后疫苗接种活动的头三个月期间,妇产科医护人员(HCWs)的 COVID-19 疫苗接种率。共有 662 名符合条件的 HCWs,包括参加江苏省研讨会的 250 名 HCWs(第 1 组)和南京鼓楼医院妇产科的 412 名 HCWs(第 2 组),受邀回答 23 个问题的问卷。共有 618 名(93.4%)HCWs 完成了问卷。第 1 组的疫苗接种率高于第 2 组(87.2%[197/226]比 74.2%[291/392],χ2=14.436, <0.001)。总体而言,488 名(79.0%)HCWs 接种了 COVID-19 疫苗,130 名(21.0%)拒绝接种。488 名接种者中有三分之一是在与他人协商或雇主要求后才接种疫苗的。调整后的逻辑回归分析表明,接种下降与对疫苗安全性的担忧有关(OR 1.920,95%CI 1.196-3.082;=0.007)。COVID-19 疫苗接种下降的主要原因包括对疫苗安全性、备孕、妊娠或哺乳期的担忧。这些结果表明,需要更多关于 COVID-19 疫苗的安全性数据,特别是在孕妇或哺乳期妇女中,以促进 COVID-19 疫苗的接种接受率。此外,雇主的接种请求或强制要求可能会提高 COVID-19 疫苗的接种率。