Al-Noori Noor Mohammed, Ibraheem Noor Sahban, Abdulmunem Mohammed Majid
Department of Oral Surgery and Periodontology, College of Dentistry, Mustansiriyah University, Baghdad, Iraq.
Saudi Dent J. 2021 Nov;33(7):674-678. doi: 10.1016/j.sdentj.2020.04.011. Epub 2020 May 7.
Smoking is harmful to all organs of the human body and can affect nerve response to local anesthesia.This study aimed to determine the effect of cigarette smoking on the amount and onset of local anesthesia, as well as the chief complaint (symptomatic and asymptomatic), number of cigarettes, and duration of smoking.
A selective clinical case-control study carried out at the Oral Surgery Clinic of the Teaching Hospital at the College of Dentistry. One hundred and three male patients participated in the study, and they were divided into two groups (55 smokers and 48 nonsmokers). The patients received a local anesthetic agent (2% Lidocaine) in a 1.8 ml dental cartridge. The number of cartridges and the onset time of local anesthesia were detailed for each patient in a special case sheet prepared for this study.
There was a statistically significant difference between the smoker and nonsmoker groups regarding the amount of local anesthetic solution (p = .041) with a higher amount needed in the smoker group; however, the onset of action showed no significant difference between the two groups (p = 0.983). The symptomatic cases in smokers needed a higher amount of local anesthesia than the asymptomatic cases with a statistically significant difference (p = 0.002). There was no relationship between daily cigarette consumption and the amount of local anesthetic solution (p = .054) and also the onset of local anesthesia (p = .938). The duration of smoking has no significant relationship with onset time (p = .480) and the amount of local anesthesia (p = .418).
The amount of local anesthesia used in smoker patients was higher than that in nonsmoker patients, especially if there were symptoms like pain. The duration of smoking and daily cigarette consumption had no effect on the amount and the onset of local anesthesia.
吸烟对人体所有器官都有害,且会影响神经对局部麻醉的反应。本研究旨在确定吸烟对局部麻醉的用量和起效时间的影响,以及主要症状(有症状和无症状)、吸烟量和吸烟时长。
在牙科学院教学医院口腔外科诊所进行了一项选择性临床病例对照研究。103名男性患者参与了该研究,他们被分为两组(55名吸烟者和48名不吸烟者)。患者接受了一支1.8毫升牙用注射器中的局部麻醉剂(2%利多卡因)。在为本研究准备的一份特殊病例表中详细记录了每位患者使用的注射器数量和局部麻醉的起效时间。
吸烟者和不吸烟者在局部麻醉溶液用量方面存在统计学显著差异(p = 0.041),吸烟者组所需用量更高;然而,两组之间的起效时间没有显著差异(p = 0.983)。吸烟者中有症状的病例比无症状病例需要更高剂量的局部麻醉,差异具有统计学显著性(p = 0.002)。每日吸烟量与局部麻醉溶液用量(p = 0.054)以及局部麻醉的起效时间(p = 0.938)之间均无关联。吸烟时长与起效时间(p = 0.480)和局部麻醉用量(p = 0.418)均无显著关系。
吸烟患者使用的局部麻醉量高于不吸烟患者,尤其是在存在疼痛等症状时。吸烟时长和每日吸烟量对局部麻醉的用量和起效时间均无影响。