Cardiovascular Diseases Research Center, Department of Cardiology, School of Medicine, Birjand University of Medical Sciences, Birjand, Iran.
Clinical Research Development Unit of Razi Hospital, Birjand University of Medical Sciences, Birjand, Iran.
Pan Afr Med J. 2021 Sep 30;40:67. doi: 10.11604/pamj.2021.40.67.31546. eCollection 2021.
Adverse consequences of the coronavirus disease 2019 (COVID-19) vaccination which have been reported in scientific papers are varied. One possible but rare consequence is myocarditis, which may have a diversity of clinical manifestations. We report a case of a 70-year-old man who presented to the hospital for some syncope, 3 days after his first COVID-19 AstraZeneca Vaccination. Initial electrocardiogram (ECG) showed a long QT interval (QTc = 600 milliseconds). Laboratory tests revealed elevated troponin and lack of evidence of viral infection. Further investigations revealed the vaccine-induced myocarditis and arrhythmias linked to it. Within one week of magnesium treatment, the QT interval was completely corrected, and the patient discharged with no typical syncope attacks. This case like the previous reported one confirms that myocarditis is a complication of COVID-19 vaccine, but implies its clinical manifestations may be varied and even may happen after the single dose of vaccination.
在科学文献中报告的与 2019 年冠状病毒病（COVID-19）疫苗相关的不良后果是多种多样的。一种可能但罕见的后果是心肌炎，其可能具有多种临床表现。我们报告了一例 70 岁男性病例，该患者在首次接种阿斯利康 COVID-19 疫苗后 3 天因一些晕厥到医院就诊。初始心电图（ECG）显示 QT 间期延长（QTc = 600 毫秒）。实验室检查显示肌钙蛋白升高，且无病毒感染的证据。进一步的检查显示疫苗引起的心肌炎及其相关的心律失常。在镁治疗 1 周内，QT 间期完全纠正，患者出院且无典型晕厥发作。与之前报告的病例一样，该病例证实心肌炎是 COVID-19 疫苗的一种并发症，但也意味着其临床表现可能多种多样，甚至可能在单次接种疫苗后发生。
