• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

糖尿病患者毛霉菌病的风险:一项系统综述。

Risk of Mucormycosis in Diabetes Mellitus: A Systematic Review.

作者信息

Khanna Manish, Challa Sabitha, Kabeil Ahmed S, Inyang Bithaiah, Gondal Faisal J, Abah Godwin A, Minnal Dhandapani Mahesh, Manne Manasa, Mohammed Lubna

机构信息

Internal Medicine/Family Medicine, California Institute of Behavioral Neurosciences & Psychology, Fairfield, USA.

Medicine, Sri Ramachandra Institute of Higher Education and Research, Chennai, IND.

出版信息

Cureus. 2021 Oct 16;13(10):e18827. doi: 10.7759/cureus.18827. eCollection 2021 Oct.

DOI:10.7759/cureus.18827
PMID:34804684
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC8592794/
Abstract

Hyperglycemia or diabetes mellitus (DM) is a disorder of the endocrine system. In this condition, the body is insulin-deficient or resistant to insulin. Due to insulin deficiency or resistance, the body is unable to process sugar. The worldwide prevalence of diabetes mellitus is rising substantially. Hyperglycemia makes the immune system weak, which increases the risk of infection in a diabetic patient. Fungal infection is more common in DM. Mucormycosis is a rare fungal infection in a healthy individual, but in DM, it can cause severe complications and even be fatal if not treated adequately and timely. In our literature review, a total of 19 published articles from the PubMed database and Google Scholar were included. We combed the PubMed database and Google Scholar by using various inclusion and exclusion criteria. The result of the review study shows the increased risk of mucormycosis in a diabetic patient.

摘要

高血糖或糖尿病是一种内分泌系统紊乱疾病。在这种情况下,身体要么胰岛素分泌不足,要么对胰岛素产生抵抗。由于胰岛素缺乏或抵抗,身体无法处理糖分。糖尿病在全球的患病率正在大幅上升。高血糖会使免疫系统变弱,这增加了糖尿病患者感染的风险。真菌感染在糖尿病患者中更为常见。毛霉菌病在健康个体中是一种罕见的真菌感染,但在糖尿病患者中,它会导致严重并发症,如果得不到充分及时的治疗甚至会致命。在我们的文献综述中,共纳入了来自PubMed数据库和谷歌学术的19篇已发表文章。我们使用各种纳入和排除标准对PubMed数据库和谷歌学术进行了梳理。综述研究结果显示糖尿病患者发生毛霉菌病的风险增加。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/825e/8592794/1ba35f6811c8/cureus-0013-00000018827-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/825e/8592794/1ba35f6811c8/cureus-0013-00000018827-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/825e/8592794/1ba35f6811c8/cureus-0013-00000018827-i01.jpg

相似文献

1
Risk of Mucormycosis in Diabetes Mellitus: A Systematic Review.糖尿病患者毛霉菌病的风险:一项系统综述。
Cureus. 2021 Oct 16;13(10):e18827. doi: 10.7759/cureus.18827. eCollection 2021 Oct.
2
Diabetic Ketoacidosis (DKA), a Leading Risk Factor for Mucormycosis (Black Fungus), during the Era of Coronavirus Disease-2019 (COVID-19): An Overview.糖尿病酮症酸中毒(DKA),在 2019 冠状病毒病(COVID-19)时代,是毛霉菌病(黑真菌)的主要危险因素:概述。
Curr Diabetes Rev. 2023;19(1):e150322202260. doi: 10.2174/1573399818666220315162424.
3
A systematic review on SARS-CoV-2-associated fungal coinfections.关于 SARS-CoV-2 相关真菌感染的系统评价。
J Med Virol. 2022 Jan;94(1):99-109. doi: 10.1002/jmv.27358. Epub 2021 Oct 5.
4
Folic acid supplementation and malaria susceptibility and severity among people taking antifolate antimalarial drugs in endemic areas.在流行地区,服用抗叶酸抗疟药物的人群中,叶酸补充剂与疟疾易感性和严重程度的关系。
Cochrane Database Syst Rev. 2022 Feb 1;2(2022):CD014217. doi: 10.1002/14651858.CD014217.
5
Mucormycosis in COVID-19: A systematic review of cases reported worldwide and in India.COVID-19 相关毛霉菌病:全球及印度病例报告的系统综述。
Diabetes Metab Syndr. 2021 Jul-Aug;15(4):102146. doi: 10.1016/j.dsx.2021.05.019. Epub 2021 May 21.
6
COVID-19-Associated Rhinocerebral Mucormycosis, an Incidental Finding or a Matter of Concern - Mixed-Method Systematic Review.新型冠状病毒肺炎相关鼻脑毛霉菌病:偶然发现还是值得关注的问题——混合方法系统评价
Infect Drug Resist. 2024 Jan 31;17:387-402. doi: 10.2147/IDR.S445458. eCollection 2024.
7
COVID-19 and Mucormycosis: A Black Fungus Disaster?新型冠状病毒肺炎与毛霉菌病:一场黑真菌灾难?
Indian J Dermatol. 2022 Sep-Oct;67(5):535-538. doi: 10.4103/ijd.ijd_17_22.
8
A systematic review of mucormycosis cases in COVID-19: Is it an unholy trilogy of COVID-19, diabetes mellitus, and corticosteroids?对 COVID-19 患者毛霉病病例的系统评价:它是 COVID-19、糖尿病和皮质类固醇的“邪恶三联征”吗?
J Family Med Prim Care. 2022 Jun;11(6):2573-2580. doi: 10.4103/jfmpc.jfmpc_1934_21. Epub 2022 Jun 30.
9
Black fungus immunosuppressive epidemic with Covid-19 associated mucormycosis (zygomycosis): a clinical and diagnostic perspective from India.新冠疫情相关毛霉菌病(接合菌病):来自印度的临床和诊断视角下的黑木耳免疫抑制流行。
Immunogenetics. 2022 Apr;74(2):197-206. doi: 10.1007/s00251-021-01226-5. Epub 2021 Oct 1.
10
Diabetes mellitus and other underlying conditions in patients with coronavirus disease 2019 associated rhino-orbito-cerebral mucormycosis: a systematic review and meta-analysis.糖尿病和其他基础疾病与 2019 冠状病毒病相关的鼻-眶-脑毛霉菌病:系统评价和荟萃分析。
J Laryngol Otol. 2022 Sep;136(9):788-798. doi: 10.1017/S0022215122001074. Epub 2022 May 6.

引用本文的文献

1
Case Series of Post-COVID-19 Mucormycosis in Serbia/Rhino-Orbital-Cerebral Form: Surgical and Medical Treatment.塞尔维亚新冠后毛霉菌病病例系列/鼻眶脑型:手术及药物治疗
Case Rep Infect Dis. 2025 Aug 4;2025:8385268. doi: 10.1155/crdi/8385268. eCollection 2025.
2
Study of Management of Mucormycosis in COVID and Post-COVID Patients with Liposomal Amphotericin B its Outcome and Complications in a dedicated COVID Hospital from Eastern India.印度东部一家专门的新冠医院中,脂质体两性霉素B治疗新冠及新冠康复患者毛霉菌病的管理、结果及并发症研究。
Niger Med J. 2025 Jun 16;66(2):746-753. doi: 10.71480/nmj.v66i2.666. eCollection 2025 Mar-Apr.
3

本文引用的文献

1
A Rare Case of Invasive Mucormycosis in a Diabetic Patient Treated with a Short Course of Dexamethasone.一例短期使用地塞米松治疗的糖尿病患者发生侵袭性毛霉病的罕见病例。
Am J Case Rep. 2021 Jul 26;22:e932129. doi: 10.12659/AJCR.932129.
2
Diabetes, COVID 19 and mucormycosis: Clinical spectrum and outcome in a tertiary care medical center in Western India.糖尿病、COVID-19 和毛霉菌病:印度西部一家三级护理医疗中心的临床谱和结局。
Diabetes Metab Syndr. 2021 Jul-Aug;15(4):102196. doi: 10.1016/j.dsx.2021.102196. Epub 2021 Jul 3.
3
The PRISMA 2020 statement: an updated guideline for reporting systematic reviews.
Invasive Mucormycosis in a Chronic Lymphocytic Leukemia Patient on Zanubrutinib: A Case Report.
一例接受泽布替尼治疗的慢性淋巴细胞白血病患者发生侵袭性毛霉病:病例报告
Infect Drug Resist. 2025 Jul 4;18:3281-3287. doi: 10.2147/IDR.S526660. eCollection 2025.
4
Synthesis of Chitosan based nanoemulsions and their characterization and antifungal activity toward fungi causing mucormycosis.基于壳聚糖的纳米乳液的合成及其对引起毛霉病的真菌的表征和抗真菌活性。
Sci Rep. 2025 Jun 27;15(1):20326. doi: 10.1038/s41598-025-06577-7.
5
Diagnosis, clinical features, and mortality risk factors in a Chinese cohort with pulmonary mucormycosis.中国肺毛霉病队列中的诊断、临床特征及死亡风险因素
PLoS One. 2025 May 16;20(5):e0323624. doi: 10.1371/journal.pone.0323624. eCollection 2025.
6
Real-World Effectiveness and Safety of Isavuconazole Versus Amphotericin B for Patients with Invasive Mucormycosis.艾沙康唑与两性霉素B治疗侵袭性毛霉病患者的真实世界有效性和安全性
Microorganisms. 2025 Jan 1;13(1):55. doi: 10.3390/microorganisms13010055.
7
MUCORMYCOSIS: Re-emerging opportunistic fungal infections in COVID-19 pandemic times in Indian patients (South Indian) - A series of seven cases.毛霉菌病:印度患者(南印度)在新冠疫情期间重新出现的机会性真菌感染——七例系列病例
J Oral Maxillofac Pathol. 2024 Jul-Sep;28(3):497-505. doi: 10.4103/jomfp.jomfp_236_24. Epub 2024 Oct 15.
8
Mucormycosis and COVID-19: Unraveling the Interplay of Fungal Infection in a Global Health Crisis: An Overview.毛霉菌病与2019冠状病毒病:在全球健康危机中解析真菌感染的相互作用:概述
Infect Disord Drug Targets. 2025;25(4):e18715265310191. doi: 10.2174/0118715265310191240919060621.
9
A Causal Relationship between Type 2 Diabetes and Candidiasis through Two-Sample Mendelian Randomization Analysis.通过两样本孟德尔随机化分析探讨2型糖尿病与念珠菌病之间的因果关系。
Microorganisms. 2024 Sep 30;12(10):1984. doi: 10.3390/microorganisms12101984.
10
Breaking the mold: Insights into the clinical management and outcomes of rhinocerebral mucormycosis in adults.打破常规:成人鼻脑型毛霉菌病临床管理与结局的见解
IDCases. 2024 Jul 3;37:e02024. doi: 10.1016/j.idcr.2024.e02024. eCollection 2024.
《PRISMA 2020声明:报告系统评价的更新指南》
Syst Rev. 2021 Mar 29;10(1):89. doi: 10.1186/s13643-021-01626-4.
4
Pathophysiology of Type 2 Diabetes Mellitus.2 型糖尿病的病理生理学。
Int J Mol Sci. 2020 Aug 30;21(17):6275. doi: 10.3390/ijms21176275.
5
Rhino-orbital mucormycosis due to Apophysomyces ossiformis in a patient with diabetes mellitus: a case report.一名糖尿病患者因骨状附孢霉引起的鼻眶毛霉病:病例报告
BMC Infect Dis. 2020 Aug 18;20(1):614. doi: 10.1186/s12879-020-05337-4.
6
Successful treatment of rhino-facial mucormycosis in a diabetic patient.糖尿病患者鼻面部毛霉菌病的成功治疗
Med Mycol Case Rep. 2020 Jan 16;27:64-67. doi: 10.1016/j.mmcr.2020.01.003. eCollection 2020 Mar.
7
Invasive fungal rhinosinusitis in patients with diabetes.糖尿病患者的侵袭性真菌性鼻-鼻窦炎
J Infect Dev Ctries. 2018 Sep 30;12(9):787-793. doi: 10.3855/jidc.9699.
8
Mass Cytometry Identifies Distinct Subsets of Regulatory T Cells and Natural Killer Cells Associated With High Risk for Type 1 Diabetes.质谱细胞术鉴定与 1 型糖尿病高危相关的调节性 T 细胞和自然杀伤细胞的不同亚群。
Front Immunol. 2019 May 3;10:982. doi: 10.3389/fimmu.2019.00982. eCollection 2019.
9
Global Epidemiology of Mucormycosis.毛霉病的全球流行病学
J Fungi (Basel). 2019 Mar 21;5(1):26. doi: 10.3390/jof5010026.
10
Disease Entities in Mucormycosis.毛霉病中的疾病实体
J Fungi (Basel). 2019 Mar 14;5(1):23. doi: 10.3390/jof5010023.