Spyridakis Evangelos, Weidner Bryan, Nguyen Chi K, Ergun-Longmire Berrin
Department of Pediatrics, The University of Florida, The Studer Family Children's Hospital at Sacred Heart, Pensacola, FL, USA.
Pediatric Surgery, The Studer Family Children's Hospital at Sacred Heart, Pensacola, FL, USA.
AME Case Rep. 2021 Oct 25;5:33. doi: 10.21037/acr-20-168. eCollection 2021.
Ovarian neoplasms constitute 1% of childhood tumors. The majority of them are teratomas and usually are asymptomatic or present with paraneoplastic syndromes. Our case is a 16-year-old female who presented with chronic abdominal pain, virilization and oligomenorrhea and found to have a complex cystic mass of the left ovary, more likely cystic teratoma on abdomen and pelvis CT. Further work-up revealed significantly elevated serum total and free testosterone. The patient subsequently underwent left salpingo-oophorectomy confirming the radiological findings. Within two week after surgery, serum testosterone normalized and the patient started having regular menstrual cycles. In summary, ovarian teratomas should be include in the differential diagnosis of abdominal pain and menstrual abnormalities in female adolescents. Further studies are needed to determine the role of ovarian-sparing surgery in this patient population.
卵巢肿瘤占儿童肿瘤的1%。其中大多数是畸胎瘤,通常无症状或伴有副肿瘤综合征。我们的病例是一名16岁女性,表现为慢性腹痛、男性化和月经过少,腹部和盆腔CT发现左卵巢有一个复杂的囊性肿块,很可能是囊性畸胎瘤。进一步检查显示血清总睾酮和游离睾酮显著升高。患者随后接受了左侧输卵管卵巢切除术,证实了影像学检查结果。术后两周内,血清睾酮恢复正常,患者开始有规律的月经周期。总之,卵巢畸胎瘤应纳入女性青少年腹痛和月经异常的鉴别诊断。需要进一步研究以确定保留卵巢手术在该患者群体中的作用。