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对内耳和外耳毛细胞的影响。

Effects on the inner and outer hair cells.

作者信息

Rydmarker S, Nilsson P

机构信息

Department of Otolaryngology and Experimental Research, University of Lund, Malmö General Hospital, Sweden.

出版信息

Acta Otolaryngol Suppl. 1987;441:25-43. doi: 10.3109/00016488709124799.

Abstract

Scanning electron microscopy has improved the quality of the information obtained on morphological changes in the organ of Corti caused by noise exposure and the development of non-standard statistical methods has made accurate quantitative evaluation of these morphological changes possible. Many different types of hair cell damage were observed in noise-exposed cochleas, and the changes found in the inner and outer hair cells were found to differ considerably. Both analysis of impulse noise and continuous noise gave different results when applied to the inner hair cells as compared to when applied to the outer hair cells. However, of the outer hair cell rows the outermost was most frequently damaged by both impulse noise and continuous noise. The results of this investigation support previous suggestions that the inner and outer hair cell rows should be evaluated separately in experimental research.

摘要

扫描电子显微镜提高了关于噪声暴露引起的柯蒂氏器形态变化所获信息的质量,非标准统计方法的发展使得对这些形态变化进行准确的定量评估成为可能。在噪声暴露的耳蜗中观察到许多不同类型的毛细胞损伤,并且发现内毛细胞和外毛细胞的变化有很大差异。与应用于外毛细胞相比,将脉冲噪声和连续噪声分析应用于内毛细胞时得出了不同的结果。然而,在外侧毛细胞排中,最外层的毛细胞最常受到脉冲噪声和连续噪声的损伤。这项研究的结果支持了先前的建议,即在实验研究中应分别对内毛细胞排和外毛细胞排进行评估。

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