Department of Traditional Medicine, School of Persian Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Musculoskeletal Research Group and Tumor Biology, Chair of Vegetative Anatomy, Institute of Anatomy, Faculty of Medicine, Ludwig-Maximilian-University Munich, Munich, Germany.
J Tissue Eng Regen Med. 2022 Feb;16(2):91-109. doi: 10.1002/term.3267. Epub 2021 Dec 7.
Silk worm (Bombyx Mori) protein, have been considered as potential materials for a variety of advanced engineering and biomedical applications for decades. Recently, silkworm silk has gained significant importance in research attention mainly because of its remarkable and exceptional mechanical properties. Silk has already been shown to have unique interactions with cells in tissues through bio-recognition units. The natural silk contains fibroin and sericin and has been used in various tissues of the human body (skin, bone, nerve, and so on). Besides, silk also still has anti-cancer, anti-tyrosinase, anti-coagulant, anti-oxidant, anti-bacterial, and anti-diabetic properties. This article is supposed to describe the diverse biomedical capabilities of B. Mori silk as the appropriate biomaterial among the assorted natural and artificial polymers that are presently accessible, and ideal for usage in regenerative medicine fields.
蚕（Bombyx Mori）蛋白已被认为是具有各种先进工程和生物医学应用潜力的材料，这一观点已存在数十年。最近，由于其显著而独特的机械性能，家蚕丝在研究中的重要性日益增加。已经证明，丝通过生物识别单元与组织中的细胞具有独特的相互作用。天然丝包含丝素和丝胶，已被用于人体的各种组织（皮肤、骨骼、神经等）。此外，丝还具有抗癌、抗酪氨酸酶、抗凝血、抗氧化、抗菌和抗糖尿病的特性。本文旨在描述 B. Mori 丝作为目前可获得的各种天然和人工聚合物中的合适生物材料，在再生医学领域具有广泛的应用潜力。
