SUNY/College of Optometry, Department of Biological and Vision Sciences, New York City 10036, USA.
Schepens Eye Research Institute of Mass. Eye & Ear, Boston 02114, USA.
Vision Res. 2022 Feb;191:107967. doi: 10.1016/j.visres.2021.107967. Epub 2021 Nov 19.
Vergence and accommodation have been critical areas of investigation in those with mild traumatic brain injury (mTBI). In this mini-review, the major laboratory studies in the area using objective assessment of vergence and accommodative dynamics in this population are discussed. These include the basic findings, their diagnostic and therapeutic implications, potential study limitations, and suggested future research directions. All studies provided important new information, and insights, into the area. There were two key outcomes of the reviewed studies common to both the vergence and accommodative systems in those with mTBI. First, most dynamic parameter's responsivity at baseline was abnormal: it was slowed, delayed, and/or inaccurate as compared to the normative control data. Second, most of the abnormal dynamic parameter's responsivity could be remediated, at least in part, following a short period of oculomotor-based vision therapy, thus demonstrating considerable residual neuroplasticity in the damaged, human brain.
在轻度创伤性脑损伤（mTBI）患者中，辐辏和调节是关键的研究领域。在这个小型综述中，讨论了该领域使用客观评估辐辏和调节动力学的主要实验室研究。这些研究包括基本发现、其诊断和治疗意义、潜在的研究局限性以及建议的未来研究方向。所有研究都为该领域提供了重要的新信息和见解。在 mTBI 患者中，辐辏和调节系统的两个关键研究结果是共同的。首先，大多数动态参数的基础反应异常：与正常对照数据相比，反应速度减慢、延迟和/或不准确。其次，大多数异常动态参数的反应性可以通过短期基于眼球运动的视觉疗法来纠正，至少部分纠正，从而证明受损人脑具有相当大的神经可塑性。
