Thiagarajan Preethi, Ciuffreda Kenneth J
Retina Foundation of the Southwest, 9600 N Central Expy, Ste 200, Dallas, TX 75231.
J Rehabil Res Dev. 2014;51(2):175-91. doi: 10.1682/JRRD.2013.01.0027.
Accommodative dysfunction is a common oculomotor sequelae of mild traumatic brain injury (mTBI). This study evaluated a range of dynamic (objective) and static (subjective) measures of accommodation in 12 nonstrabismic individuals with mTBI and near vision-related symptoms before and after oculomotor training (OMT) and placebo (P) training (6 wk, two sessions per week, 3 h of training each). Following OMT, the dynamics of accommodation improved markedly. Clinically, there was a significant increase in the maximum accommodative amplitude both monocularly and binocularly. In addition, the near vision symptoms reduced along with improved visual attention. None of the measures were found to change significantly following P training. These results provide evidence for a significant positive effect of the accommodatively based OMT on accommodative responsivity. Such improvement is suggestive of oculomotor learning, demonstrating considerable residual brain-visual system plasticity in the adult compromised brain.
调节功能障碍是轻度创伤性脑损伤(mTBI)常见的动眼神经后遗症。本研究评估了12名患有mTBI且有近视力相关症状的非斜视个体在进行动眼神经训练(OMT)和安慰剂(P)训练(6周,每周两次,每次训练3小时)前后一系列动态(客观)和静态(主观)调节指标。OMT后,调节的动态指标显著改善。临床上,单眼和双眼的最大调节幅度均显著增加。此外,近视力症状减轻,视觉注意力改善。P训练后未发现任何指标有显著变化。这些结果为基于调节的OMT对调节反应性有显著积极作用提供了证据。这种改善提示了动眼神经学习,表明在成年受损大脑中存在相当大的残余脑-视觉系统可塑性。