COVID-19 疫苗接种后复杂性区域疼痛综合征（CRPS）临床症状急剧恶化：病例系列研究。
Acute worsening of clinical presentation in CRPS after SARS-CoV-2 (COVID-19) vaccination: a case series.
机构信息
Research Assistant, Department of Anesthesiology, Critical Care & Pain Management, Hospital for Special Surgery, New York, NY 10021, USA.
Attending Physician, Department of Anesthesiology, Critical Care & Pain Management, Hospital for Special Surgery, New York, NY 10021, USA.
出版信息
Pain Manag. 2022 Apr;12(3):249-254. doi: 10.2217/pmt-2021-0089. Epub 2021 Nov 23.
We present the acute worsening of clinical presentation in complex regional pain syndrome (CRPS), following mRNA-based COVID-19 vaccination. We report the case series of three patients diagnosed with CRPS type I who presented with acute worsening of symptoms after mRNA-based COVID-19 vaccination and their medical management. The acute clinical worsening after mRNA-based COVID-19 vaccination was transient and effectively managed with adjustment of individualized therapy in all three patients. The mortality and morbidity of COVID-19 infection are serious, and vaccination is recommended in the general population, including patients with a diagnosis of CRPS. However, clinicians should be aware of the possibility that there may be a clinical worsening CRPS after mRNA-based COVID-19 vaccination.
我们报告了三例 I 型复杂性区域疼痛综合征（CRPS）患者，他们在接受基于 mRNA 的 COVID-19 疫苗接种后出现了临床症状的急性恶化，并对其进行了治疗。这三例患者在接受基于 mRNA 的 COVID-19 疫苗接种后出现了急性临床恶化，但经过个体化治疗的调整后，症状均得到了缓解。基于 mRNA 的 COVID-19 疫苗接种后的急性临床恶化是暂时的，所有患者的症状都得到了有效控制。COVID-19 感染的死亡率和发病率都很严重，建议在普通人群中接种疫苗，包括被诊断为 CRPS 的患者。然而，临床医生应该意识到，在接受基于 mRNA 的 COVID-19 疫苗接种后，CRPS 可能会出现临床恶化。
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