Department of Otorhinolaryngology, National Health Insurance Service Ilsan Hospital, Goyang, Korea.
Hum Vaccin Immunother. 2021 Dec 2;17(12):5126-5128. doi: 10.1080/21645515.2021.2013085. Epub 2021 Dec 13.
Coronavirus disease 2019 (COVID-19) is caused by severe acute respiratory syndrome coronavirus 2 and presents with pneumonia as the most frequent and serious manifestation. COVID-19 vaccination is an important and urgent interest globally due to COVID-19's rapid spread and high rates of mortality and morbidity. Vestibular neuritis (VN) is an acute vestibular syndrome that causes acute and spontaneous vertigo due to unilateral vestibular deafferentiation, leading to nausea or vomiting and unsteadiness that can last from days to weeks. Reactivation of latent type 1 herpes simplex virus, autoimmune disorders, and microvascular ischemia are hypothesized to be etiologies. Herein, the case of a 54-year-old man who developed VN within three days after COVID-19 vaccination is presented. There have been no reports of VN after vaccination for COVID-19 or other viral diseases. Although the association between VN and COVID-19 vaccination remains unclear, clinicians should be aware that VN may occur as an adverse event of COVID-19 vaccination.
新型冠状病毒病（COVID-19）是由严重急性呼吸系统综合征冠状病毒 2 引起的，肺炎是最常见和最严重的表现。由于 COVID-19 的快速传播以及高死亡率和发病率，COVID-19 疫苗接种成为全球的重要且紧急的关注点。前庭神经炎（VN）是一种急性前庭综合征，由于单侧前庭去传入导致急性和自发性眩晕，导致恶心或呕吐和不稳，可持续数天至数周。潜伏的 1 型单纯疱疹病毒的再激活、自身免疫性疾病和微血管缺血被认为是病因。本文介绍了一例 54 岁男性，他在 COVID-19 疫苗接种后三天内发生 VN。尚无 COVID-19 疫苗接种或其他病毒性疾病后发生 VN 的报道。虽然 VN 与 COVID-19 疫苗接种之间的关联仍不清楚，但临床医生应该意识到 VN 可能是 COVID-19 疫苗接种的不良反应事件。
